Inhibition of amyloid-β plaque formation by α-synuclein

被引：0
|
作者：
Teresa Bachhuber
Natalie Katzmarski
Joanna F McCarter
Desiree Loreth
Sabina Tahirovic
Frits Kamp
Claudia Abou-Ajram
Brigitte Nuscher
Alberto Serrano-Pozo
Alexandra Müller
Marco Prinz
Harald Steiner
Bradley T Hyman
Christian Haass
Melanie Meyer-Luehmann
机构：
[1] Adolf Butenandt Institute,Department of Biochemistry
[2] Ludwig-Maximilians University,Department of Neurology
[3] Neurocenter,Department of Metabolic Biochemistry
[4] University of Freiburg,undefined
[5] Faculty of Biology,undefined
[6] University of Freiburg,undefined
[7] German Center for Neurodegenerative Diseases (DZNE),undefined
[8] Ludwig-Maximilians University,undefined
[9] MassGeneral Institute for Neurodegenerative Disease,undefined
[10] Massachusetts General Hospital and Harvard Medical School,undefined
[11] Institute of Neuropathology,undefined
[12] University of Freiburg,undefined
[13] Centre for Biological Signalling Studies (BIOSS),undefined
[14] University of Freiburg,undefined
[15] Munich Cluster for Systems Neurology (SyNergy),undefined
来源：
Nature Medicine | 2015年 / 21卷
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摘要：
The introduction of α-synuclein into mouse models of Alzheimer's disease, either by intracerebral injection or transgenic overexpression, is found to inhibit the formation of hippocampal amyloid-β plaques.
引用
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页码：802 / 807
页数：5
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