The Role of ASXL1/2 and Their Associated Proteins in Malignant Hematopoiesis

[1] Greenblatt SM(2014)Chromatin modifiers and the promise of epigenetic therapy in acute leukemia Leukemia. 28 1396-1406

[2] Nimer SD(2010)Hematopoietic stem cell: self-renewal versus differentiation Wiley Interdiscip Rev Syst Biol Med 2 640-653

[3] Seita J(2012)The role of mutations in epigenetic regulators in myeloid malignancies Nat Rev Cancer 12 599-612

[4] Weissman IL(2013)Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer Nat Rev Genet 14 765-780

[5] Shih AH(2019)Clonal Hematopoiesis with Oncogenic Potential (CHOP): Separation from CHIP and Roads to AML International Journal of Molecular Sciences 20 789-1478

[6] Abdel-Wahab O(2014)Age-related mutations associated with clonal hematopoietic expansion and malignancies Nat Med 20 1472-2487

[7] Patel JP(2014)Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence N Engl J Med 371 2477-2498

[8] Levine RL(2014)Age-related clonal hematopoiesis associated with adverse outcomes N Engl J Med 371 2488-16

[9] Plass C(2005)Myelodysplastic syndrome Annu Rev Med 56 1-4851

[10] Pfister SM(2008)Myelodysplastic syndromes Blood. 111 4841-515

[1] Greenblatt SM(2014)Chromatin modifiers and the promise of epigenetic therapy in acute leukemia Leukemia. 28 1396-1406

[2] Nimer SD(2010)Hematopoietic stem cell: self-renewal versus differentiation Wiley Interdiscip Rev Syst Biol Med 2 640-653

[3] Seita J(2012)The role of mutations in epigenetic regulators in myeloid malignancies Nat Rev Cancer 12 599-612

[4] Weissman IL(2013)Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer Nat Rev Genet 14 765-780

[5] Shih AH(2019)Clonal Hematopoiesis with Oncogenic Potential (CHOP): Separation from CHIP and Roads to AML International Journal of Molecular Sciences 20 789-1478

[6] Abdel-Wahab O(2014)Age-related mutations associated with clonal hematopoietic expansion and malignancies Nat Med 20 1472-2487

[7] Patel JP(2014)Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence N Engl J Med 371 2477-2498

[8] Levine RL(2014)Age-related clonal hematopoiesis associated with adverse outcomes N Engl J Med 371 2488-16

[9] Plass C(2005)Myelodysplastic syndrome Annu Rev Med 56 1-4851

[10] Pfister SM(2008)Myelodysplastic syndromes Blood. 111 4841-515