Immunomodulatory activity of SGI-110, a 5-aza-2′-deoxycytidine-containing demethylating dinucleotide

被引：0
作者：
Sandra Coral
Giulia Parisi
Hugues J. M. G. Nicolay
Francesca Colizzi
Riccardo Danielli
Elisabetta Fratta
Alessia Covre
Pietro Taverna
Luca Sigalotti
Michele Maio
机构：
[1] Centro di Riferimento Oncologico,Cancer Bioimmunotherapy Unit
[2] Istituto Toscano Tumori,Division of Medical Oncology and Immunotherapy, Department of Oncology, University Hospital of Siena
[3] Astex Pharmaceuticals,undefined
[4] Inc.,undefined
来源：
Cancer Immunology, Immunotherapy | 2013年 / 62卷
关键词：
DNA hypomethylating agent; Cancer; Immunotherapy; Epigenetics;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：605 / 614
页数：9
相关论文
共 50 条
  • [31] 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation:: mechanistic studies and their implications for cancer therapy
    Christman, JK
    ONCOGENE, 2002, 21 (35) : 5483 - 5495
  • [32] Safety and clinical activity of 5-aza-2′-deoxycytidine (decitabine) with or without Hyper-CVAD in relapsed/refractory acute lymphocytic leukaemia
    Benton, Christopher B.
    Thomas, Deborah A.
    Yang, Hui
    Ravandi, Farhad
    Rytting, Michael
    O'Brien, Susan
    Franklin, Anna R.
    Borthakur, Gautam
    Dara, Samuel
    Kwari, Monica
    Pierce, Sherry R.
    Jabbour, Elias
    Kantarjian, Hagop
    Garcia-Manero, Guillermo
    BRITISH JOURNAL OF HAEMATOLOGY, 2014, 167 (03) : 356 - 365
  • [33] 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy
    Judith K Christman
    Oncogene, 2002, 21 : 5483 - 5495
  • [34] Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation
    Patra, S. K.
    Bettuzzi, S.
    BIOCHEMISTRY-MOSCOW, 2009, 74 (06) : 613 - 619
  • [35] Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2′-deoxycytidine and DNA-demethylation
    S. K. Patra
    S. Bettuzzi
    Biochemistry (Moscow), 2009, 74 : 613 - 619
  • [36] Synthesis and Crosslinking Activity of 4-N-(4,5′,8-Trimethylpsoralen-4′-ylmethyl)-2′-deoxycytidine-containing Oligodeoxyribonucleotides
    Kobori, Akio
    Kohji, Tomita
    Nagae, Yuko
    Yamayoshi, Asako
    Murakami, Akira
    CHEMISTRY LETTERS, 2012, 41 (08) : 804 - 805
  • [37] The Importance of Validating the Demethylating Effect of 5-aza-2′-deoxycytidine in Model Species (A Comment on Cook et al., "DNA Methylation and Sex Allocation in the Parasitoid Wasp Nasonia vitripennis")
    Ellers, Jacintha
    Visser, Michael
    Marien, Janine
    Kraaijeveld, Ken
    Lammers, Mark
    AMERICAN NATURALIST, 2019, 194 (03) : 422 - 431
  • [38] 5-AZA-2′-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer
    Saldova, Radka
    Dempsey, Eugene
    Perez-Garay, Marta
    Marino, Karina
    Watson, Jenny A.
    Blanco-Fernandez, Alfonso
    Struwe, Weston B.
    Harvey, David J.
    Madden, Stephen F.
    Peracaula, Rosa
    McCann, Amanda
    Rudd, Pauline M.
    EPIGENETICS, 2011, 6 (11) : 1362 - 1372
  • [39] Comparison of DNMT1 inhibitors by methylome profiling identifies unique signature of 5-aza-2′ deoxycytidine
    Mackin, Sarah-Jayne
    O'Neill, Karla M.
    Walsh, Colum P.
    EPIGENOMICS, 2018, 10 (08) : 1085 - 1101
  • [40] MAGED4 Expression in Glioma and Upregulation in Glioma Cell Lines with 5-Aza-2'-Deoxycytidine Treatment
    Zhang, Qing-Mei
    Shen, Ning
    Xie, Sha
    Bi, Shui-Qing
    Luo, Bin
    Lin, Yong-Da
    Fu, Jun
    Zhou, Su-Fang
    Luo, Guo-Rong
    Xie, Xiao-Xun
    Xiao, Shao-Wen
    ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 15 (08) : 3495 - 3501
12345