A clustered plasticity model of long-term memory engrams

被引：0
|
作者：
Arvind Govindarajan
Raymond J. Kelleher
Susumu Tonegawa
机构：
[1] The Picower Institute for Learning and Memory,Department of Biology and Department of Brain and Cognitive Sciences
[2] Howard Hughes Medical Institute,the Center for Human Genetic Research and the Department of Neurology
[3] RIKEN-MIT Neuroscience Research Center,undefined
[4] Massachusetts Institute of Technology,undefined
[5] Massachusetts General Hospital,undefined
[6] Richard B. Simches Research Center,undefined
[7] CPZN-6234,undefined
来源：
Nature Reviews Neuroscience | 2006年 / 7卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Long-term memory formation is associated with bidirectional changes in synaptic strength that require enhanced protein synthesis. Govindarajan, Kelleher and Tonegawa describe a model by which translation-dependent plasticity at synapses that are clustered in a dendritic branch facilitates the formation of long-term memory engrams.
引用
收藏
页码：575 / 583
页数：8
相关论文
共 50 条
  • [41] Role of atypical protein kinases in maintenance of long-term memory and synaptic plasticity
    Borodinova, A. A.
    Zuzina, A. B.
    Balaban, P. M.
    BIOCHEMISTRY-MOSCOW, 2017, 82 (03) : 243 - 256
  • [42] Enhanced long-term memory and increased mushroom body plasticity in Heliconius butterflies
    Young, Fletcher J.
    Anton, Amaia Alcalde
    Melo-Florez, Lina
    Couto, Antoine
    Foley, Jessica
    Monllor, Monica
    McMillan, W. Owen
    Montgomery, Stephen H.
    ISCIENCE, 2024, 27 (02)
  • [43] Organization and Priming of Long-term Memory Representations with Two-phase Plasticity
    Luboeinski, Jannik
    Tetzlaff, Christian
    COGNITIVE COMPUTATION, 2023, 15 (04) : 1211 - 1230
  • [44] Computational models of memory consolidation and long-term synaptic plasticity during sleep
    Renno-Costa, Cesar
    Costa da Silva, Ana Claudia
    Blanco, Wilfredo
    Ribeiro, Sidarta
    NEUROBIOLOGY OF LEARNING AND MEMORY, 2019, 160 : 32 - 47
  • [45] Ubiquitin-dependent protein degradation is necessary for long-term plasticity and memory
    Bal', N. V.
    Balaban, P. M.
    NEUROCHEMICAL JOURNAL, 2015, 9 (04) : 237 - 244
  • [46] Regulation of gene expression and its role in long-term memory and synaptic plasticity
    Tully, T.
    Proceedings of the National Academy of Sciences of the United States of America, 94 (09):
  • [47] Role of atypical protein kinases in maintenance of long-term memory and synaptic plasticity
    A. A. Borodinova
    A. B. Zuzina
    P. M. Balaban
    Biochemistry (Moscow), 2017, 82 : 243 - 256
  • [48] Organization and Priming of Long-term Memory Representations with Two-phase Plasticity
    Jannik Luboeinski
    Christian Tetzlaff
    Cognitive Computation, 2023, 15 : 1211 - 1230
  • [49] Tadalafil restores long-term memory and synaptic plasticity in mice with hepatic encephalopathy
    Rocha Franca, Maria Eduarda
    Luna Gomes Ramos, Renata Kelly
    Oliveira, Wilma Helena
    Duarte-Silva, Eduardo
    Rocha Araujo, Shyrlene Meyre
    Los, Deniele Bezerra
    Peixoto, Christina Alves
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 379
  • [50] Modeling clustered long-term survivors using marginal mixture cure model
    Niu, Yi
    Song, Lixin
    Liu, Yufeng
    Peng, Yingwei
    BIOMETRICAL JOURNAL, 2018, 60 (04) : 780 - 796
12345