A clustered plasticity model of long-term memory engrams

被引：0
|
作者：
Arvind Govindarajan
Raymond J. Kelleher
Susumu Tonegawa
机构：
[1] The Picower Institute for Learning and Memory,Department of Biology and Department of Brain and Cognitive Sciences
[2] Howard Hughes Medical Institute,the Center for Human Genetic Research and the Department of Neurology
[3] RIKEN-MIT Neuroscience Research Center,undefined
[4] Massachusetts Institute of Technology,undefined
[5] Massachusetts General Hospital,undefined
[6] Richard B. Simches Research Center,undefined
[7] CPZN-6234,undefined
来源：
Nature Reviews Neuroscience | 2006年 / 7卷
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摘要：
Long-term memory formation is associated with bidirectional changes in synaptic strength that require enhanced protein synthesis. Govindarajan, Kelleher and Tonegawa describe a model by which translation-dependent plasticity at synapses that are clustered in a dendritic branch facilitates the formation of long-term memory engrams.
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页码：575 / 583
页数：8
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