Sympathetic hyperactivity in patients with ulcerative colitis

被引：0
作者：
Simona Maule
Giulia Pierangeli
Sabina Cevoli
Daniela Grimaldi
Paolo Gionchetti
Giovanni Barbara
Fernando Rizzello
Vincenzo Stanghellini
Roberto Corinaldesi
Massimo Campieri
Pietro Cortelli
机构：
[1] S. Vito Hospital,Autonomic Unit
[2] University of Turin,Autonomic Unit, Dept. of Neurosciences
[3] University of Bologna,Dipartimento di Scienze Neurologiche
[4] Università di Bologna,Dept. of Gastroenterology
[5] University of Bologna,undefined
来源：
Clinical Autonomic Research | 2007年 / 17卷
关键词：
ulcerative colitis; sympathetic nervous system; power spectrum analysis; heart rate variability; autonomic nervous system;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Hypo and hyperactivity of the autonomic nervous system have been associated with chronic bowel inflammation diseases. We investigated the autonomic function in 11 patients with chronic ulcerative colitis (UC) and 17 healthy controls by means of cardiovascular autonomic tests and heart rate variability. Autonomic responses were normal in patients and controls. At rest, LF/HF ratios were significantly (P < 0.05) higher in chronic UC patients (2.4 ± 1.6) compared to controls (1.2 ± 1.0). Our results suggest a higher sympathetic tone at rest in patients with chronic UC.
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页码：217 / 220
页数：3
相关论文
共 40 条
  • [1] Bernstein CN(1993)Rectal substance P concentrations are increased in ulcerative colitis but not in Crohn’s disease Am J Gastroenterol 88 908-913
  • [2] Robert ME(1980)Abnormalities of vasoactive intestinal polypeptide-containing nerves in Crohn’s disease Gastroenterology 79 853-860
  • [3] Eysselein VE(1994)Cardiovascular autonomic dysfunction in normotensive awake subjects with obstructive sleep apnoea syndrome Clin Auton Res 4 57-62
  • [4] Bishop AE(2005)Autonomic neural regulation of immunity J Intern Med 257 156-166
  • [5] Polak JM(1965)An epidemiological study of ulcerative colitis and regional enteritis in the Oxford area Gut 6 311-324
  • [6] Bryant MG(2006)Sympathetic overactivity in active ulcerative colitis: effects of clonidine Am J Physiol Regul Integr Comp Physiol 290 R224-R232
  • [7] Cortelli P(2000)Altered function of the hypothalamic stress axes in patients with moderately active systemic lupus erythematosus. The hypothalamus-automic nervous system axis J Rheumatol 27 903-910
  • [8] Parchi P(1996)The enteric nervous system N England J Med 334 1106-1115
  • [9] Sforza E(1988)Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinis, calcitonin gene-related peptide and other neuropeptides Neuroscience 24 739-768
  • [10] Czura CJ(1993)Autonomic vagal nerve dysfunction in patients with ulcerative colitis Scand J Gastroenterol 28 638-642
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