Genetic Architecture of Olfactory Behavior in Drosophila melanogaster: Differences and Similarities Across Development

被引：0
作者：
N. J. Lavagnino
G. H. Arya
A. Korovaichuk
J. J. Fanara
机构：
[1] Facultad de Ciencias Exactas y Naturales,Departamento de Ecología, Genética y Evolución
[2] Universidad de Buenos Aires,Department of Systems Neuroscience
[3] Instituto de Ecología,Department of Biology
[4] Genética y Evolución (IEGEBA),undefined
[5] CONICET,undefined
[6] Cajal Institute,undefined
[7] Consejo Superior de Investigaciones Científicas,undefined
[8] North Carolina State University,undefined
[9] W. M. Keck Center for Behavioral Biology,undefined
[10] North Carolina State University,undefined
来源：
Behavior Genetics | 2013年 / 43卷
关键词：
Olfactory behavior; Development; Genetic architecture;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In the holometabolous insect Drosophila melanogaster, genetic, physiological and anatomical aspects of olfaction are well known in the adult stage, while larval stages olfactory behavior has received some attention it has been less studied than its adult counterpart. Most of these studies focus on olfactory receptor (Or) genes that produce peripheral odor recognition. In this paper, through a loss-of-function screen using P-element inserted lines and also by means of expression analyses of larval olfaction candidate genes, we extended the uncovering of the genetic underpinnings of D. melanogaster larval olfactory behavior by demonstrating that larval olfactory behavior is, in addition to Or genes, orchestrated by numerous genes with diverse functions. Also, our results point out that the genetic architecture of olfactory behavior in D. melanogaster presents a dynamic and changing organization across environments and ontogeny.
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页码：348 / 359
页数：11
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