Concomitant blockade of P2X-receptors and ecto-nucleotidases by P2-receptor antagonists: functional consequences in rat vas deferens

被引:0
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作者
R. Bültmann
Marie Trendelenburg
Florin Tuluc
Henning Wittenburg
Klaus Starke
机构
[1] Pharmakologisches Institut,
[2] Hermann-Herder-Strasse 5,undefined
[3] D-79104 Freiburg i.Br.,undefined
[4] Germany,undefined
关键词
Key words Rat vas deferens; P2X-receptor; Ecto-nucleotidases; P2-receptor antagonists; NF023; Suramin; Evans blue; Reactive red 2;
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摘要
In order to assess the consequences of a concomitant blockade of P2X-receptors and ecto-nucleotidases, effects of 13 P2-receptor antagonists were investigated on contractions of the rat vas deferens elicited by α,β-methylene ATP (α,β-MeATP) and ATP and on the removal of ATP from the incubation medium by vas deferens tissue.
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页码:339 / 344
页数:5
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