CNS activity of Pokeweed Anti-viral Protein (PAP) in mice infected with Lymphocytic Choriomeningitis Virus (LCMV)

被引:0
作者
Fatih M Uckun
Larisa Rustamova
Alexei O Vassilev
Heather E Tibbles
Alexander S Petkevich
机构
[1] Parker Hughes Center for Clinical Immunology,
[2] Research Institute for Epidemiology and Microbiology,undefined
来源
BMC Infectious Diseases | / 5卷
关键词
Antiviral Activity; Spring Leaf; Intracerebral Injection; Lassa Fever; Lymphocytic Choriomeningitis Virus;
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[1]  
Irvin JD(1992)Pokeweed antiviral protein: ribosome inactivation and therapeutic applications Pharmacol Ther 55 279-302
[2]  
Uckun FM(2004)A 13-week subchronic intravaginal toxicity study of pokeweed antiviral protein in mice Phytomedicine 11 342-351
[3]  
D'Cruz OJ(2004)Antiviral activity of ribosome inactivating proteins in medicine Mini Rev Med Chem 4 523-543
[4]  
Waurzyniakt B(2001)Active center cleft residues of pokeweed antiviral protein mediate its high-affinity binding to the ribosomal protein L3 Biochemistry 40 9104-9114
[5]  
Uckun FM(2003)High resolution X-ray structure of potent anti-HIV pokeweed antiviral protein-III Biochem Pharmacol 65 1709-1717
[6]  
Parikh BA(2003)Structure-based design and engineering of a nontoxic recombinant pokeweed antiviral protein with potent anti-human immunodeficiency virus activity Antimicrob Agents Chemother 47 1052-1061
[7]  
Turner NE(2001)Binding interactions between the active center cleft of recombinant pokeweed antiviral protein and the alpha-sarcin/ricin stem loop of ribosomal RNA J Biol Chem 276 24075-24081
[8]  
Rajamohan F(2001)Pokeweed antiviral protein: a potential nonspermicidal prophylactic antiviral agent Fertil Steril 75 106-114
[9]  
Ozer Z(2000)X-ray crystallographic analysis of pokeweed antiviral protein-II after reductive methylation of lysine residues Biochem Biophys Res Commun 275 549-552
[10]  
Mao C(2000)Expression of biologically active recombinant pokeweed antiviral protein in methylotrophic yeast Pichia pastoris Protein Expr Purif 18 193-201