Hairy cell leukemia

被引:0
作者
Ronan Swords
Francis Giles
机构
[1] University College Hospital Galway,Department of Haematology
[2] The University of Texas M.D. Anderson Cancer Centre,Department of Leukaemia — Unit 428
来源
Medical Oncology | 2007年 / 24卷
关键词
Hairy cell leukemia; purine analogs; pathophysiology; treatment;
D O I
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学科分类号
摘要
Hairy cell leukemia (HCL) is a chronic B-cell lymphoproliferative disorder characterized by pancytopenia and variable infiltration of the reticuloendothelial system with “hairy” lymphocytes. HCL is more common in men than women and has a median age of diagnosis of 52 yr. Typically, patients with HCL respond well to purine analog-based therapy. The purpose of this review will be to establish the current status of HCL with respect to its pathophysiology, diagnosis, management, and future directions.
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页码:7 / 15
页数:8
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