Erythropoietin in stem cell transplantation

被引：0
作者：
CB Miller
HM Lazarus
机构：
[1] Johns Hopkins Oncology Center,Department of Medicine
[2] Ireland Cancer Centre,undefined
[3] University Hospitals of Cleveland,undefined
来源：
Bone Marrow Transplantation | 2001年 / 27卷
关键词：
anemia; stem cell transplantation; erythropoietin;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Anemia is universal after allogeneic and autologous stem cell transplantation, with both increased red cell utilization and decreased production playing a role. This anemia sometimes is associated with a relative erythropoietin deficiency. In allogeneic stem cell transplantation, randomized trials have demonstrated improved erythropoiesis and a decrease in red cell transfusions in recombinant human erythropoietin (rHuEPO)-treated patients. Studies of rHuEPO in patients undergoing autologous stem cell transplants, however, have not shown a benefit. The role of rHuEPO in stem cell mobilization and treatment of delayed erythropoiesis has yet to be defined and further studies are needed. Bone Marrow Transplantation (2001) 27, 1011–1016.
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页码：1011 / 1016
页数：5
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