Reverse chemomodulatory effects of the SIRT1 activators resveratrol and SRT1720 in Ewing’s sarcoma cells: resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer activity

[21] Bueso-Ramos C(2010)Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer Int J Cancer 127 257-154

[22] Takada Y(1999)Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway Carcinogenesis 20 237-1219

[23] Gaur U(2014)Small molecule SIRT1 activators for the treatment of aging and age-related diseases Trends Pharmacol Sci 35 146-220

[24] Nair AS(2013)Evidence for a common mechanism of SIRT1 regulation by allosteric activators Science 339 1216-84

[25] Shishodia S(1997)Cancer chemopreventive activity of resveratrol, a natural product derived from grapes Science 275 218-463

[26] Aggarwal BB(2004)Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin’s lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis Mol Cancer Ther 3 71-159

[27] Brunet A(2008)Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator Cancer Cell 13 454-878

[28] Sweeney LB(2012)Molecular pathogenesis of Ewing sarcoma: new therapeutic and transcriptional targets Annu Rev Pathol 7 145-998

[29] Sturgill JF(2010)Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha Mol Cell 38 864-36394

[30] Chua KF(2004)Curcumin and resveratrol induce apoptosis and nuclear translocation and activation of p53 in human neuroblastoma Anticancer Res 24 987-148

[21] Bueso-Ramos C(2010)Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer Int J Cancer 127 257-154

[22] Takada Y(1999)Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway Carcinogenesis 20 237-1219

[23] Gaur U(2014)Small molecule SIRT1 activators for the treatment of aging and age-related diseases Trends Pharmacol Sci 35 146-220

[24] Nair AS(2013)Evidence for a common mechanism of SIRT1 regulation by allosteric activators Science 339 1216-84

[25] Shishodia S(1997)Cancer chemopreventive activity of resveratrol, a natural product derived from grapes Science 275 218-463

[26] Aggarwal BB(2004)Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin’s lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis Mol Cancer Ther 3 71-159

[27] Brunet A(2008)Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator Cancer Cell 13 454-878

[28] Sweeney LB(2012)Molecular pathogenesis of Ewing sarcoma: new therapeutic and transcriptional targets Annu Rev Pathol 7 145-998

[29] Sturgill JF(2010)Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha Mol Cell 38 864-36394

[30] Chua KF(2004)Curcumin and resveratrol induce apoptosis and nuclear translocation and activation of p53 in human neuroblastoma Anticancer Res 24 987-148