Reverse chemomodulatory effects of the SIRT1 activators resveratrol and SRT1720 in Ewing’s sarcoma cells: resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer activity

[1] Ahmad KA(2004)Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intracellular milieu nonpermissive for death execution Cancer Res 64 1452-1459

[2] Clement MV(2013)Synergistic anti-proliferative effect of resveratrol and etoposide on human hepatocellular and colon cancer cell lines Eur J Pharmacol 718 34-40

[3] Hanif IM(2010)Ewing’s sarcoma Lancet Oncol 11 184-192

[4] Pervaiz S(2012)Are sirtuins viable targets for improving healthspan and lifespan? Nat Rev Drug Discov 11 443-461

[5] Amiri F(2007)Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells Blood 109 2293-2302

[6] Zarnani AH(2004)Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science 303 2011-2015

[7] Zand H(2013)Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice BMC Complement Altern Med 13 6-1312

[8] Koohdani F(2008)Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: the roles of caspase-6 and p53 Cancer Biol Ther 7 1305-598

[9] Jeddi-Tehrani M(2011)Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cells Br J Haematol 155 588-681

[10] Vafa M(2006)Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies Pharmacol Rev 58 621-7222

[1] Ahmad KA(2004)Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intracellular milieu nonpermissive for death execution Cancer Res 64 1452-1459

[2] Clement MV(2013)Synergistic anti-proliferative effect of resveratrol and etoposide on human hepatocellular and colon cancer cell lines Eur J Pharmacol 718 34-40

[3] Hanif IM(2010)Ewing’s sarcoma Lancet Oncol 11 184-192

[4] Pervaiz S(2012)Are sirtuins viable targets for improving healthspan and lifespan? Nat Rev Drug Discov 11 443-461

[5] Amiri F(2007)Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells Blood 109 2293-2302

[6] Zarnani AH(2004)Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science 303 2011-2015

[7] Zand H(2013)Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice BMC Complement Altern Med 13 6-1312

[8] Koohdani F(2008)Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: the roles of caspase-6 and p53 Cancer Biol Ther 7 1305-598

[9] Jeddi-Tehrani M(2011)Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cells Br J Haematol 155 588-681

[10] Vafa M(2006)Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies Pharmacol Rev 58 621-7222