Morphological Organization of the Mouse Preimplantation Embryo

被引：0
作者：
Toshihiko Fujimori
Yoko Kurotaki
Kouji Komatsu
Yo-ichi Nabeshima
机构：
[1] Kyoto University,Department of Pathology and Tumor Biology, Graduate School of Medicine
[2] Japan Science and Technology Agency (JST),Core Research for Evolutional Science and Technology (CREST)
[3] Kiba Park Clinic,undefined
来源：
Reproductive Sciences | 2009年 / 16卷
关键词：
Blastocyst; mouse; differentiation; axis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
During the 4 days after fertilization, the mouse embryo proceeds in its development within the zona pellucida and reaches the blastocyst stage, when a newly formed embryonic-abembryonic (E-Ab) axis is settled before implantation. The previous findings suggested that the shape of the zona pellucida, which may function as an environmental cue for the embryo proper, is a major factor affecting the specification of the blastocyst axis orientation. The characteristics of the cells were not dependent on the shape of the zona pellucida. It is suggested that the division order of cells is under certain rules, and the differentiation of cells is dependent on the relative position of blastomeres in later stages.
引用
收藏
页码：171 / 177
页数：6
相关论文
共 76 条
[1]  
Niwa H(2005)Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation Cell 123 917-929
[2]  
Toyooka Y(2005)Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst Development 132 2093-2102
[3]  
Shimosato D(2007)Stochastic patterning in the mouse pre-implantation embryo Development 134 4219-4231
[4]  
Strumpf D(1987)A quantitative analysis of cell allocation to trophectoderm and inner cell mass in the mouse blastocyst Dev Biol 119 520-531
[5]  
Mao CA(1978)Time of commitment of inside cells isolated from preimplantation mouse embryos J Embryol Exp Morphol 45 37-53
[6]  
Yamanaka Y(1981)The foundation of two distinct cell lineages within the mouse morula Cell 24 71-80
[7]  
Dietrich JE(1967)Development of blastomeres of mouse eggs isolated at the 4- and 8-cell stage J Embryol Exp Morphol 18 155-180
[8]  
Hiiragi T(2002)Trophectoderm growth and bilateral symmetry of the blastocyst in the mouse Hum Reprod 17 1839-1845
[9]  
Fleming TP(1997)The early blastocyst is bilaterally symmetrical and its axis of symmetry is aligned with the animal-vegetal axis of the zygote in the mouse Development 124 289-301
[10]  
Handyside AH(2006)An investigation of the origin and significance of bilateral symmetry of the pronuclear zygote in the mouse Hum Reprod 21 492-502
12345678