Monoclonal gammopathy in prostate carcinoma: A case report and review of literature

被引:3
作者
Pramanik S. [1 ,3 ]
Gazi M.J. [1 ]
Das A.K. [2 ]
Debnath N.B. [1 ]
Pal S.K. [1 ]
机构
[1] Department of General Medicine, Calcutta National Medical College, Kolkata
[2] Department of Pathology, Calcutta National Medical College, Kolkata
[3] 876 Tagore Park, Naskarhat, Kolkata
关键词
Monoclonal gammopathy; Prostate carcinoma; Serum protein electrophoresis;
D O I
10.1186/s13256-018-1811-z
中图分类号
学科分类号
摘要
Background: Monoclonal gammopathy is commonly associated with plasma cell dyscrasia. However, monoclonal gammopathy without bone marrow plasmacytosis in prostate carcinoma has rarely been reported. The association between the two conditions is not clearly established. Case presentation: We report a case of metastatic prostate carcinoma in a 65-year-old Indian man with the unusual phenomenon of monoclonal band in gamma globulin region without evidence of bone marrow plasmacytosis. Conclusions: Monoclonal gammopathy in solid tumor has seldom been reported. This case report highlights the rare association of monoclonal gammopathy with malignant prostatic carcinoma. Therefore, while investigating a case such as this, in an elderly male patient, we should always keep a lookout for any solid tumor foci after excluding multiple myeloma. © 2018 The Author(s).
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共 11 条
[1]  
Kyle R.A., Current concepts on monoclonal gammopathies, Aust NZ J Med, 22, (1992)
[2]  
Talerman A., Hije W.G., The frequency of M-components in sera of patients with solid malignant neoplasms, Br J Cancer, 27, (1973)
[3]  
Sehgal T., Sharma S., Naseem S., Varma N., Das A., Sharma S.C., Synchronous Occurrence of Prostate Carcinoma and Multiple Myeloma: A Case Report, Indian J Hematol Blood Transfus, 30, pp. 359-362, (2014)
[4]  
Huang E., Teh B.S., Saleem A., Butler E.B., Recurrence of prostate adenocarcinoma presenting with multiple myeloma simulating skeletal metastases of prostate adenocarcinoma, Urology, 60, 6, (2002)
[5]  
Kao J., Jani A.B., Vijayakumar S., Is there an association between multiple myeloma and prostate cancer?, Med Hypotheses, 63, 2, pp. 226-231, (2004)
[6]  
Niels W.C., Et al., The clinical relevance and management of monoclonal gammopathy of undetermined significance and related disorders: Recommendations from the European Myeloma Network, Haematologica, 99, 6, pp. 984-996, (2014)
[7]  
Abdul M., Hoosein N.M., Gammopathy associated with advanced prostate carcinoma, Urol Res, 23, 3, pp. 185-188, (1995)
[8]  
Migliore P.J., Alexanian R., Monoclonal gammopathy in human neoplasia, Cancer, 21, 6, pp. 1127-1131, (1968)
[9]  
Solomon A., Homogeneous (monoclonal) immunoglobulins in cancer, Am J Med, 63, 2, pp. 169-176, (1977)
[10]  
Lsobe T., Osserman E.F., Pathologic conditions associated with plasma cell dyscrasias: A study of 806 cases, Ann N y Acad Sci, 190, (1971)