Assessment of the hepatic arterial and portal venous blood flows during pregnancy with Doppler ultrasonography

被引：74

作者：

Nakai A. ^{[1
]}

Sekiya I. ^{[1
]}

Oya A. ^{[1
]}

Koshino T. ^{[1
]}

Araki T. ^{[1
]}

机构：

[1] Department of Obstetrics, Tama Nagayama Hospital, Nippon Medical School, Tama-shi, Tokyo 206-8512

来源：

Archives of Gynecology and Obstetrics | 2002年 / 266卷 / 1期

关键词：

Doppler ultrasound; Hepatic artery; Portal vein; Pregnancy;

D O I：

10.1007/PL00007495

中图分类号：

学科分类号：

摘要：

Purpose: The aim of this study was to evaluate whether the dual hepatic blood supply is altered in healthy pregnant women compared with that in non-pregnant women. Materials and methods: Flow waveforms in common hepatic artery and portal vein were obtained in 67 healthy pregnant women at 10-40 weeks gestation and 22 nonpregnant women by using Doppler ultrasonography. Results: In the nonpregnant group, the mean (SD) hepatic arterial blood flow, portal venous blood flow, and total liver blood flow were 0.57 (0.31) L/min, 1.25 (0.46) L/min, and 1.82 (0.63) L/min, respectively. In the healthy pregnant group, the portal venous blood flow and total liver blood flow significantly increased after 28 weeks gestation. However, the hepatic arterial blood flow remained unchanged during pregnancy. There was no relationship between the hepatic arterial blood flow and the portal venous blood flow. Conclusion: The results demonstrated that the hepatic perfusion increased during third trimester compared to nonpregnant level. Because the hepatic arterial blood flow remained unchanged during pregnancy, major determinant of the increase in the hepatic perfusion was the portal venous return. The data suggest that the hepatic arterial and portal venous vascular territories have regulatory mechanisms that allow for independent changes during pregnancy.

引用

页码：25 / 29

页数：4

共 32 条

[1]

Aarnoudse J.G., Houthoff H.J., Weits J., Vellinga E., Huisjes H.J., A syndrome of liver damage and intravascular coagulation in the last trimester of normotensive pregnancy. A clinical and histopathological study, Br J Obstet Gyneaecol, 93, pp. 145-155, (1986)

[2]

Bartko J.J., Carpenter W.T., On the methods and theory of reliability, J Nerv Ment Dis, 163, pp. 307-317, (1976)

[3]

Cicchetti D.V., Sparrow S.A., Developing criteria for establishing interrater reliability of specific items: Applications to assessment of adaptive behavior, Am J Ment Defic, 86, pp. 127-137, (1981)

[4]

Condon R.E., Nyhus L.M., Chapman N.D., Harkings H.N., Portal vein and hepatic artery interactions: Studies in the isolated, perfused liver, Gastroenterology, 43, pp. 547-556, (1962)

[5]

Fisher A.J., Paulson E.K., Kliewer M.K., Delong D.M., Nelson R.C., Doppler sonography of the portan vein and hepatic artery: Measurement of a prandial effect in healthy subjects, Radiology, 207, pp. 711-715, (1998)

[6]

Gaiani S., Bolondi L., Bassi A.L., Santi V., Zironi G., Barbara L., Effect of meal on portal hemodynamics in healthy humans and in patients with chronic liver disease, Hepatology, 9, pp. 815-819, (1989)

[7]

Goldberg R.E.A., Rade C., Knelson M., Haaga J., Minkin S., The response of the portal vein to an oral glucose load, J Clin Ultrasound, 18, pp. 691-695, (1990)

[8]

Greenway C.V., Stark R.D., Hepatic vascular bad, Physiol Rev, 51, pp. 23-65, (1971)

[9]

Greenway C.V., Oshiro G., Intrahepatic distribution of portal and hepatic arterial blood flows in unanesthetized cats and dogs and the effects of portal occlusion, J Physiol, 227, pp. 473-485, (1972)

[10]

Iwao T., Toyonaga A., Oho K., Tayama C., Masumoto H., Sakai T., Sato M., Tanikawa K., Value of Doppler ultrasound parameters of portal vein and hepatic artery in the diagnosis of cirrhosis and portal hypertension, Am J Gastroenterol, 92, pp. 1012-1017, (1997)

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