Fabrication of microcomposites based on silk sericin and monetite for bone tissue engineering

被引：0
作者：
S. Weslen Vedakumari
R. Jayalakshmi
C. G. Sanjayan
B. Jayavardhini
K. Arya
R. Murugesan
机构：
[1] Chettinad Academy of Research and Education,Faculty of Allied Health Sciences
来源：
Polymer Bulletin | 2020年 / 77卷
关键词：
Biomaterials; Sericin; Monetite; Composite materials; Osteoblast; Bone graft;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In the present study, silk sericin–monetite microcomposites (SS–MM) were prepared using a simple and cost-effective method. Hemolytic assay was performed to determine the blood compatibility of SS–MM. MTT assay was carried out using MG-63 osteoblasts, to determine the cytocompatibility and proliferative efficacy of SS–MM. Alkaline phosphatase activity was studied to examine the osteogenic potency of the prepared microcomposites. The results obtained showed that the SS–MM can be effectively used as a bone graft for tissue engineering applications.
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页码：475 / 481
页数：6
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