Current state of ventricular assist devices

被引：41
作者：
Caccamo M. [1 ]
Eckman P. [1 ]
John R. [2 ]
机构：
[1] Department of Medicine, Division of Cardiovascular Medicine, University of Minnesota, Minneapolis, MN
[2] Department of Cardiothoracic Surgery, Division of Surgery, University of Minnesota, Minneapolis, MN 55455
来源：
Current Heart Failure Reports | 2011年 / 8卷 / 2期
关键词：
Bridge to transplant; Complications; Continuous-flow device; Destination therapy; Device; Heart failure; Heart transplantation; Left ventricular assist device; LVAD; Mechanical support; Pulsatile-flow device;
D O I：
10.1007/s11897-011-0050-z
中图分类号：
学科分类号：
摘要：
Left ventricular assist device (LVAD) support is an accepted treatment of patients with end-stage heart failure. The increased applicability and excellent results with LVADs have revolutionized the treatment options available for such patients. Success with LVADs as bridge-to-transplant therapy has led to their successful use as an alternate to a transplant (ie, as destination therapy [DT]). The use of these devices as DT represents a relatively newer but growing indication. Until recently, most patients who have undergone LVAD implantation have been supported by pulsatile devices. Newer continuous-flow (CF) pumps have resulted in superior outcomes, including significantly reduced complication rates with improved durability over first-generation pulsatile design pumps. However, as with all new technology, the newer LVADs have introduced management challenges that were either unimportant or absent with pulsatile LVADs. This article reviews the current state of left ventricular devices, focusing on the CF pumps that currently dominate the field, including clinical outcomes, the physiologic and pathologic effects that are associated with CF pumps, and their unique management issues and complications. © 2011 Springer Science+Business Media, LLC.
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页码：91 / 98
页数：7
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