Effects of Chronic Exercise Training on Inflammatory Markers in Australian Overweight and Obese Individuals in a Randomized Controlled Trial

被引：0
作者：
Suleen S. Ho
Satvinder S. Dhaliwal
Andrew P. Hills
Sebely Pal
机构：
[1] Curtin University,School of Public Health, Curtin Health Innovation Research Institute
[2] Griffith University,Mater Mother’s Hospital, Mater Medical Research Institute, Conjoint Appointment with Griffith Health Institute
来源：
Inflammation | 2013年 / 36卷
关键词：
obesity; overweight; tumor necrosis factor-α; interleukin-6; exercise training;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Physical activity has been shown to lower levels of inflammatory markers. However, results are inconsistent, indicating different modes of exercise may have different effects on inflammatory cytokines. We aimed to investigate the effects of 12 weeks of moderate-intensity aerobic, resistance, or combination exercise on TNF-α and IL-6 compared to no exercise in overweight and obese individuals. TNF-α levels were significantly decreased at week 12 compared to baseline by 20.8 % in the Aerobic group (p = 0.011), 26.9 % in the Resistance group (p = 0.0001), and 32.6 % in the Combination group (p = 0.003). Levels of TNF-α were significantly lower in the Combination compared to the Control group after 12 weeks of exercise training (−22.6 %, p = 0.025) when adjusting for baseline levels. Twelve weeks of moderate-intensity aerobic, resistance, but mainly combination exercise training decreased TNF-α in overweight and obese individuals compared to no exercise. Therefore, combination exercise training may be physiologically relevant in decreasing the risk of developing chronic diseases.
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页码：625 / 632
页数：7
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  • [1] Bruunsgaard H(2005)Physical activity and modulation of systemic low-level inflammation Journal of Leukocyte Biology 78 819-835
  • [2] Haffner SM(2007)Abdominal adiposity and cardiometabolic risk: do we have all the answers? The American Journal of Medicine 120 S10-17
  • [3] Kern PA(2001)Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance American Journal of Physiology, Endocrinology and Metabolism 280 745-751
  • [4] Ranganathan S(2004)Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial American Journal of Clinical Nutrition 79 544-551
  • [5] Li C(2007)Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women International Journal of Obesity 31 996-1003
  • [6] Wood L(2008)Effects of exercise training on inflammatory markers in patients with heart failure Heart Failure Reviews 13 39-49
  • [7] Ranganathan G(2001)Changes in tumor necrosis factor-α system and insulin sensitivity during an exercise training program in obese women with normal and impaired glucose tolerance European Journal of Endocrinology 145 273-290
  • [8] Nicklas BJ(2002)Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year Circulation 105 804-809
  • [9] Ambrosius W(2008)Obesity, depression, and chronic low-grade inflammation in women with polycystic ovary syndrome Brain, Behavior, and Immunity 22 177-184
  • [10] Messier SP(2008)Visceral obesity and plasma glucose-insulin homeostasis: contributions of interleukin-6 and tumor necrosis factor-α in men Journal of Clinical Endocrinology and Metabolism 93 1931-1938
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