There is documentation of the use of opium derived products in the ancient history of the Assyrians: the Egyptians; in the sixth century AD by the Roman Dioscorides; and by Avicenna (980–1037). Reference to opium like products is made by Paracelsus and by Shakespeare. Charles Louis Derosne and Fredrich Wilhelm Adam Serturner isolated morphine from raw opium in 1802 and 1806 respectively, and it was Sertürner who named the substance morphine, after Morpheus, the Greek God of dreams. By the middle 1800s, Opium and related opioid derived products were the source of a major addiction in USA, and to some extent in the United Kingdom. Opioid products are of major therapeutic value in the treatment of pain from injury, post surgery, intractable pain conditions, and some forms of terminal cancer.
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London Sch Hyg & Trop Med, Anthropol African Biosci Res Grp, London WC1E 9SH, EnglandLondon Sch Hyg & Trop Med, Anthropol African Biosci Res Grp, London WC1E 9SH, England
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Harvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USAHarvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USA
Dalal, Rahul S.
Norgard, Bente Mertz
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Harvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USA
Odense Univ Hosp, Ctr Clin Epidemiol, Odense, Denmark
Univ Southern Denmark, Dept Clin Res, Res Unit Clin Epidemiol, Odense, Denmark
Tufts Univ, Div Gastroenterolgy & Hepatol, Sch Med, Boston, MA USAHarvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USA
Norgard, Bente Mertz
Zegers, Floor D.
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Odense Univ Hosp, Ctr Clin Epidemiol, Odense, Denmark
Univ Southern Denmark, Dept Clin Res, Res Unit Clin Epidemiol, Odense, DenmarkHarvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USA
Zegers, Floor D.
Kjeldsen, Jens
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Odense Univ Hosp, Dept Med Gastroenterol S, Odense, Denmark
Univ Southern Denmark, Dept Clin Res, Res Unit Med Gastroenterol, Odense, DenmarkHarvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USA
Kjeldsen, Jens
Friedman, Sonia
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Odense Univ Hosp, Ctr Clin Epidemiol, Odense, Denmark
Univ Southern Denmark, Dept Clin Res, Res Unit Clin Epidemiol, Odense, Denmark
Tufts Univ, Div Gastroenterolgy & Hepatol, Sch Med, Boston, MA USAHarvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USA
Friedman, Sonia
Allegretti, Jessica R.
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Harvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USAHarvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USA
Allegretti, Jessica R.
Lund, Ken
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Odense Univ Hosp, Ctr Clin Epidemiol, Odense, Denmark
Univ Southern Denmark, Dept Clin Res, Res Unit Clin Epidemiol, Odense, DenmarkHarvard Med Sch, Brighamand Womens Hosp, Dept Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USA
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Erasmus MC Canc Inst, Dept Med Oncol, POB 5201, NL-3008 AE Rotterdam, NetherlandsErasmus MC Canc Inst, Dept Med Oncol, POB 5201, NL-3008 AE Rotterdam, Netherlands
Oldenmenger, Wendy H.
Smitt, Peter A. E. Sillevis
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Erasmus MC, Dept Neurol, Rotterdam, NetherlandsErasmus MC Canc Inst, Dept Med Oncol, POB 5201, NL-3008 AE Rotterdam, Netherlands
Smitt, Peter A. E. Sillevis
de Raaf, Pleun J.
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Erasmus MC Canc Inst, Dept Med Oncol, POB 5201, NL-3008 AE Rotterdam, NetherlandsErasmus MC Canc Inst, Dept Med Oncol, POB 5201, NL-3008 AE Rotterdam, Netherlands
de Raaf, Pleun J.
van der Rijt, Carin C. D.
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Erasmus MC Canc Inst, Dept Med Oncol, POB 5201, NL-3008 AE Rotterdam, Netherlands
Netherlands Comprehens Canc Org, Utrecht, NetherlandsErasmus MC Canc Inst, Dept Med Oncol, POB 5201, NL-3008 AE Rotterdam, Netherlands
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Stellenbosch Univ, Fac Med & Hlth Sci, Dept Med, Div Clin Pharmacol, Cape Town, South AfricaStellenbosch Univ, Fac Med & Hlth Sci, Dept Med, Div Clin Pharmacol, Cape Town, South Africa
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Stanford Univ, Sch Med, Dept Anesthesia, Div Pain Management, Palo Alto, CA 94304 USAStanford Univ, Sch Med, Dept Anesthesia, Div Pain Management, Palo Alto, CA 94304 USA
Younger, Jarred W.
Chu, Larry F.
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机构:Stanford Univ, Sch Med, Dept Anesthesia, Div Pain Management, Palo Alto, CA 94304 USA
Chu, Larry F.
D'Arcy, Nicole T.
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机构:Stanford Univ, Sch Med, Dept Anesthesia, Div Pain Management, Palo Alto, CA 94304 USA
D'Arcy, Nicole T.
Trott, Kiley E.
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Stanford Univ, Sch Arts & Sci, Dept Human Biol, Palo Alto, CA 94304 USAStanford Univ, Sch Med, Dept Anesthesia, Div Pain Management, Palo Alto, CA 94304 USA
Trott, Kiley E.
Jastrzab, Laura E.
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机构:Stanford Univ, Sch Med, Dept Anesthesia, Div Pain Management, Palo Alto, CA 94304 USA
Jastrzab, Laura E.
Mackey, Sean C.
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机构:Stanford Univ, Sch Med, Dept Anesthesia, Div Pain Management, Palo Alto, CA 94304 USA