A global assessment of cancer genomic alterations in epigenetic mechanisms

被引：0

作者：

Muhammad A Shah

Emily L Denton

Cheryl H Arrowsmith

Mathieu Lupien

Matthieu Schapira

机构：

[1] University of Toronto,Structural Genomics Consortium

[2] MaRS Centre,Princess Margaret Cancer Centre and Department of Medical Biophysics

[3] South Tower,Department of Pharmacology and Toxicology

[4] University of Toronto,undefined

[5] University of Toronto,undefined

[6] 1 King’s College Circle,undefined

[7] Courant Institute,undefined

[8] New York University,undefined

来源：

Epigenetics & Chromatin | / 7卷

关键词：

Epigenetics; Pan-cancer; Chromatin; Mutation; Amplification; RNA-seq;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 859 条

[1]

Baylin SB(2011)A decade of exploring the cancer epigenome - biological and translational implications Nat Rev Cancer 11 726-734

[2]

Jones PA(2012)Cancer genetics and epigenetics: two sides of the same coin? Cancer Cell 22 9-20

[3]

You JS(2007)Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug Nat Biotechnol 25 84-90

[4]

Jones PA(2005)FDA drug approval summary: azacitidine (5-azacytidine, Vidaza) for injectable suspension Oncologist 10 176-182

[5]

Marks PA(2013)Molecular pathways: protein methyltransferases in cancer Clin Cancer Res 19 6344-6350

[6]

Breslow R(2014)Targeting bromodomains: epigenetic readers of lysine acetylation Nat Rev Drug Discov 13 337-356

[7]

Kaminskas E(2012)Molecular biology. genetic events that shape the cancer epigenome Science 336 1513-1514

[8]

Farrell AT(2013)Interplay between the cancer genome and epigenome Cell 153 38-55

[9]

Wang YC(2013)Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host Nat Rev Cancer 13 497-510

[10]

Sridhara R(2013)Drugging cancer genomes Nat Rev Drug Discov 12 889-890