Estimation of bronchial tree zones involved in the formation of human forced expiratory wheezes

被引：0

作者：

Korenbaum V.I. ^{[1
,2
]}

Pochekutova I.A. ^{[1
]}

Safronova M.A. ^{[1
]}

机构：

[1] Il’ichev Pacific Oceanological Institute, Far Eastern Branch, Russian Academy of Sciences, Vladivostok

[2] Far Eastern Federal University, Vladivostok

来源：

Human Physiology | 2015年 / 41卷 / 1期

基金：

俄罗斯基础研究基金会;

关键词：

dynamic compression; forced expiration; peak frequency; statistical modeling; Strouhal coefficient; vortex shedding; wheezes;

D O I：

10.1134/S036211971406005X

中图分类号：

学科分类号：

摘要：

Forced expiratory wheezes (FEWs) are used for the diagnosis of bronchial obstruction; however, there is no clarity about the mechanisms and possible localization of their formation. The aim of the study was to clarify the sites of FEW formation at bronchial levels in different types of dynamic compression. The peak frequencies of the mid- (400–600 Hz) and high-frequency (more than 600 Hz) FEWs of the maximum power and the flow rate at the mouth were measured in a sample of 85 healthy male volunteers whose ages varied between 16 and 23 years. Strouhal coefficients were calculated for various bronchial tree levels according to Weibel’s morphometry. It is shown that, for FEWs formed by vortex shedding with Strouhal coefficients 0.2–0.3, the trend is to shift their formation zone to the proximal region with an increase in the degree of dynamic compression of the airways. For the most reliable estimates of dynamic compression, the main region of formation of mid-frequency FEWs is the area of exit of the intrathoracic portion of the trachea into its outer part and bifurcation of the trachea, while the most probable formation zone of early high-frequency FEWs is bifurcations of the primary bronchi and the trachea. © 2015, Pleiades Publishing, Inc.

引用

页码：54 / 61

页数：7

共 29 条

[1]

Kuznetsova V.K., Mechanics of breathing, Rukovodstvo po klinicheskoi fiziologii dykhaniya, (1980)

[2]

Kraman S.S., The forced expiratory wheeze. Its site of origin and possible association with lung compliance, Respiration, 44, (1983)

[3]

Forgacs P., The functional basis of pulmonary sounds, Chest, 73, 3, (1978)

[4]

Pochekutova I.A., Korenbaum V.I., Kulakov Y.V., Et al., Significance of spectral and time parameters of forced expiratory sound in evaluating bronchial patency, Hum. Physiol., 27, 4, (2001)

[5]

Fiz J.A., Jane R., Izquierdo J., Et al., Analysis of forced wheezes in asthma patients, Respiration, 73, (2006)

[6]

Gavriely N., Kelly K.B., Groberg J.B., Loring S.H., Forced expiratory wheezes are a manifestation of air flow limitation, J. Appl. Physiol., 62, (1987)

[7]

Shabtai-Musih Y., Grotberg J.B., Gavriely N., Spectral content of forced expiratory wheezes during air, He, and SF6 breathing in normal humans, J. Appl. Physiol., 72, (1992)

[8]

Hardin J.C., Patterson J.L., Monitoring the state of the human airways by analysis of respiratory sound, Acta Astronaut., 6, (1979)

[9]

Korenbaum V.I., Kulakov Y.V., Tagil'tsev A.A., Acoustic effects in the system of human breathing in forced expiration, Akust. Zh., 43, 1, (1997)

[10]

Korenbaum V.I., Pochekutova I.A., Akustikobiomekhanicheskie vzaimosvyazi v formirovanii shumov forsirovannogo vydokha cheloveka, (2006)

← 1 2 3 →