NG2 cells, a new trail for Alzheimer’s disease mechanisms?

被引:49
作者
Henrietta M Nielsen
Danyal Ek
Una Avdic
Camilla Orbjörn
Oskar Hansson
Robert Veerhuis
Annemieke JM Rozemuller
Arne Brun
Lennart Minthon
Malin Wennström
机构
[1] Lund University,Department of Clinical Sciences Malmö, Molecular Memory Research Unit
[2] Skåne University Hospital,Department of Neuroscience
[3] Mayo Clinic College of Medicine,Department of Clinical Sciences Malmö, Clinical Memory Research Unit
[4] The Memory Clinic at Skåne University Hospital (SUS),The Netherlands Brain Bank
[5] Lund University,Department of Clinical Chemistry, Neuroscience Campus Amsterdam
[6] Netherlands Institute for Neuroscience,Department of Pathology, Neuroscience Campus Amsterdam
[7] VU University Medical Center,Department of Pathology
[8] VU University Medical Center,undefined
[9] Lund University,undefined
关键词
NG2 cells; Alzheimer’s disease; Amyloid beta; Cerebrospinal fluid; Brain tissue; Cell culture;
D O I
10.1186/2051-5960-1-7
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 335 条
[1]  
Nishiyama A(1991)The primary structure of NG2, a novel membrane-spanning proteoglycan J Cell Biol 114 359-371
[2]  
Dahlin KJ(2009)NG2-positive glia in the human central nervous system Neuron Glia Biol 5 35-44
[3]  
Prince JT(1999)NG2+ glial cells: a novel glial cell population in the adult brain J Neuropathol Exp Neurol 58 1113-1124
[4]  
Johnstone SR(1999)A light and electron microscopic study of NG2 chondroitin sulfate proteoglycan-positive oligodendrocyte precursor cells in the normal and kainate-lesioned rat hippocampus Neuroscience 92 83-95
[5]  
Stallcup WB(2000)NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions J Neuroscience: Official J Soc Neurosci 20 6404-6412
[6]  
Staugaitis SM(2001)NG2 cells in the brain: a novel glial cell population Hum Cell 14 77-82
[7]  
Trapp BD(2005)Synantocytes: the fifth element J Anat 207 695-706
[8]  
Nishiyama A(2005)Two separate metalloproteinase activities are responsible for the shedding and processing of the NG2 proteoglycan in vitro Mol Cell Neurosci 29 82-96
[9]  
Chang A(2001)Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion Glia 34 296-310
[10]  
Trapp BD(2008)The ameboid phenotype of NG2 (+) cells in the region of apoptotic dentate granule neurons in trimethyltin intoxicated mice shares antigen properties with microglia/macrophages Glia 56 209-222