Heart-fatty acid-binding protein as a marker for early detection of acute myocardial infarction and stroke

被引：19
作者：
Lescuyer P. [1 ,2 ]
Allard L. [1 ]
Hochstrasser D.F. [1 ]
Sanchez J.-C. [1 ]
机构：
[1] Department of Bioinformatics and Structural Biology, Biomedical Proteomics Research Group, Geneva University, Geneva
[2] Biomedical Proteomics Research Group, DBSB/CMU, CH-1211 Geneva 4, rue Michel Servet
来源：
Molecular Diagnosis | 2005年 / 9卷 / 1期
关键词：
Infarct Size; Acute Myocardial Infarction; Mild Traumatic Brain Injury; Skeletal Muscle Injury; Mild Traumatic Brain Injury Patient;
D O I：
10.2165/00066982-200509010-00001
中图分类号：
学科分类号：
摘要：
Heart-fatty acid-binding protein (H-FABP) is a small cytosolic protein involved in intracellular fatty acid transport. This protein, highly concentrated in the heart, is quickly released into plasma after myocardial injury. Results from numerous studies suggest that H-FABP is an excellent marker for the early detection of myocardial damage. H-FABP is also expressed in the brain, although in lower concentrations than in the heart. Recent preliminary studies also investigated the usefulness of H-FABP for the diagnosis of acute and chronic neurological disorders. These potential applications of H-FABP in clinical practice are reviewed in this article, with a strong focus on the early diagnosis of acute myocardial infarction and stroke. © 2005 Adis Data Information BV. All rights reserved.
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页码：1 / 7
页数：6
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