Synthesis and characterization of Fe3O4-supported metal–organic framework MIL-101(Fe) for a highly selective and sensitive hydrogen peroxide electrochemical sensor

In this study, an electrochemical sensor for the quantification of hydrogen peroxide (H2O2) based on nafion glassy carbon electrode (NGCE) modified with MIL-101(Fe)@Fe3O4 metal–organic frameworks (MOFs) was developed. Its electrochemical performance and surface analyses were examined with various techniques. The MIL-101(Fe)@Fe3O4/NGCE sensor exhibited a well-defined redox peak towards H2O2 since the frameworks provide high electronic conductivity and easy mass transfer for target molecules. The parameters that affected the performance of the developed sensor were optimized. The proposed sensor showed a low detection limit (0.15 μM) and relatively good sensitivity (68.8312 μAmM−1 cm−2) according to the differential pulse voltammetry (DPV) method. Furthermore, the chronoamperometry (CA) method exhibited high sensitivity (556.5037 μAmM−1 cm−2) but a relatively low detection limit (1.76 μM), and the proposed sensor demonstrated excellent repeatability. Furthermore, the sensor was applied for the detection of H2O2 in industrial samples.