Induction of immune tolerance in the treatment of rheumatoid arthritis

被引:0
作者
Salvatore Albani
Eva C. Koffeman
Berent Prakken
机构
[1] Translational Research Program,Department of Pediatric Immunology
[2] Inflammatory and Infectious Diseases Center,undefined
[3] Sanford-Burnham Medical Research Institute,undefined
[4] Center for Molecular and Cellular Intervention,undefined
[5] University Medical Center Utrecht,undefined
来源
Nature Reviews Rheumatology | 2011年 / 7卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The next challenge in rheumatoid arthritis (RA) therapy is the maintenance of disease remission with a minimal-treatment regimen. In this Review the authors propose that this goal could be achieved by restoring a state of immune tolerance and discuss antigen-independent and antigen-specific approaches for the induction of tolerance in the treatment of RA.
引用
收藏
页码:272 / 281
页数:9
相关论文
共 165 条
[1]  
Alivernini S(2009)ACR70-disease activity score remission achievement from switches between all the available biological agents in rheumatoid arthritis: a systematic review of the literature Arthritis Res. Ther. 11 R163-986
[2]  
Laria A(2010)Current evidence for the management of rheumatoid arthritis with biological disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of RA Ann. Rheum. Dis. 69 976-1108
[3]  
Gremese E(2010)Rheumatoid arthritis Lancet 376 1094-652
[4]  
Zoli A(2010)The Japanese experience with biologic therapies for rheumatoid arthritis Nat. Rev. Rheumatol. 6 644-342
[5]  
Ferraccioli G(2009). Alterations in cytokine profile and dendritic cells subsets in peripheral blood of rheumatoid arthritis patients before and after biologic therapy Ann. NY Acad. Sci. 1173 334-327
[6]  
Nam JL(2010)New and future agents in the treatment of rheumatoid arthritis Discov. Med. 9 319-1045
[7]  
Scott DL(1994)Tolerance, danger, and the extended family Annu. Rev. Immunol. 12 991-200
[8]  
Wolfe F(2004)Immunotherapy: bewitched, bothered, and bewildered no more Science 305 197-216
[9]  
Huizinga TW(2004)Immune therapy for autoimmune diseases Science 305 212-604
[10]  
Takeuchi T(2005)Regulation of immunity by self-reactive T cells Nature 435 598-202