WISH-R– a fast and efficient tool for construction of epistatic networks for complex traits and diseases

被引：0
作者：
Victor A. O. Carmelo
Lisette J. A. Kogelman
Majbritt Busk Madsen
Haja N. Kadarmideen
机构：
[1] Technical University of Denmark,Quantitative and Systems Genomics Group, Department of Bio and Health Informatics
[2] University of Copenhagen,Animal Breeding, Quantitative Genetics and Systems Biology group, Department of Large Animal Sciences, Faculty of Health and Medical Sciences
[3] Rigshospitalet Glostrup,Danish Headache Center, Department of Neurology
[4] Institute of Biological Psychiatry,undefined
[5] Mental Health Centre,undefined
[6] Sct. Hans,undefined
来源：
BMC Bioinformatics | / 19卷
关键词：
Epistasis; Networks; GWAS; Complex traits; WGCNA;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 28 条
[1]  
Visscher PM(2012)Five years of GWAS discovery Am J Hum Genet 90 7-24
[2]  
Shao H(2008)Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis Proc Natl Acad Sci U S A 105 19910-19914
[3]  
Liu JZ(2015)Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations Nat Genet 47 979-986
[4]  
Manolio TA(2009)Finding the missing heritability of complex diseases Nature 461 747-753
[5]  
Phillips PC(1998)The language of gene interaction Genetics 149 1167-1171
[6]  
Mackay TFC(2014)Epistasis and quantitative traits: using model organisms to study gene-gene interactions Nat Rev Genet 15 22-33
[7]  
Cordell HJ(1995)Two-locus maximum Lod score analysis of a multifactorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes Am J Hum Genet 57 920-934
[8]  
Cox NJ(1999)Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans Nat Genet 21 213-215
[9]  
Cho JH(1998)Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1 Proc Natl Acad Sci U S A 95 7502-7507
[10]  
Fuller TF(2007)Weighted gene coexpression network analysis strategies applied to mouse weight Mamm Genome 18 463-472
123