Streptococcus pyogenes under pressure

被引:0
作者
Claire Turner
Shiranee Sriskandan
机构
[1] Imperial College London,Claire Turner and Shiranee Sriskandan are in the Department of Infectious Diseases & Immunity
[2] Hammersmith Hospital,undefined
[3] Du Cane Road,undefined
[4] London W12 0NN,undefined
[5] UK. s.sriskandan@imperial.ac.uk,undefined
来源
Nature Medicine | 2007年 / 13卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Contemporary M1 strains of Streptococcus pyogenes have acquired a DNase gene that improves the virulence of the bacterium, but its expression is repressed by the CovRS regulatory system. Walker et al. report that the bacteria are under selective pressure to mutate the covRS locus to maintain DNase expression for invasive infection (pages 982–986).
引用
收藏
页码:909 / 910
页数:1
相关论文
共 18 条
[1]  
Walker P(2007)undefined Nat. Med. 13 982-986
[2]  
Sumby AR(2006)undefined PLoS. Pathog. 2 e5-41
[3]  
Whitney EA(2007)undefined Mol. Microbiol. 64 34-1684
[4]  
Graviss FR(2005)undefined Proc. Natl. Acad. Sci. USA 102 1679-400
[5]  
DeLeo JM(2006)undefined Curr. Biol. 16 396-134
[6]  
Musser G(2004)undefined Mol. Microbiol. 51 123-1286
[7]  
Churchward P(2004)undefined Science 305 1283-790
[8]  
Sumby JT(2005)undefined J. Infect. Dis. 192 783-1054
[9]  
Buchanan RK(2001)undefined J. Infect. Dis. 183 1043-1684
[10]  
Aziz H(2006)undefined J. Infect. Dis. 193 1677-undefined