Endometrial Abnormality in Women With Polycystic Ovary Syndrome

被引:1
作者
Kewei Shang
Xiao Jia
Jie Qiao
Jihong Kang
Youfei Guan
机构
[1] Peking University Health Science Center,Department of Physiology and Pathophysiology
[2] Peking University Third Hospital,Department of Obstetrics and Gynecology
来源
Reproductive Sciences | 2012年 / 19卷
关键词
polycystic ovary syndrome; infertility; endometrial abnormality;
D O I
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中图分类号
学科分类号
摘要
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy associated with infertility and metabolic disorder in women of reproductive age. Although the clinical and biochemical features are heterogeneous with individuals, the most widely accepted clinical characteristics of PCOS are oligo- or anovulation combined with hyperandrogenism. With the higher rate of implantation failure after induction of ovulation or higher risk of spontaneous miscarriage after pregnancy, the reduced fertility is apparently attributed not only to anovulation but also to endometrial dysfunction in patients with PCOS. Here we review the features of the endometrial abnormalities in women with PCOS. The ability to improve the endometrial functions is of potential therapeutic targets to increase reproductive outcome of women with PCOS.
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页码:674 / 683
页数:9
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