Endometrial Abnormality in Women With Polycystic Ovary Syndrome

被引：1
作者：
Kewei Shang
Xiao Jia
Jie Qiao
Jihong Kang
Youfei Guan
机构：
[1] Peking University Health Science Center,Department of Physiology and Pathophysiology
[2] Peking University Third Hospital,Department of Obstetrics and Gynecology
来源：
Reproductive Sciences | 2012年 / 19卷
关键词：
polycystic ovary syndrome; infertility; endometrial abnormality;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy associated with infertility and metabolic disorder in women of reproductive age. Although the clinical and biochemical features are heterogeneous with individuals, the most widely accepted clinical characteristics of PCOS are oligo- or anovulation combined with hyperandrogenism. With the higher rate of implantation failure after induction of ovulation or higher risk of spontaneous miscarriage after pregnancy, the reduced fertility is apparently attributed not only to anovulation but also to endometrial dysfunction in patients with PCOS. Here we review the features of the endometrial abnormalities in women with PCOS. The ability to improve the endometrial functions is of potential therapeutic targets to increase reproductive outcome of women with PCOS.
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页码：674 / 683
页数：9
相关论文
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  • [1] Franks S(1995)Polycystic ovary syndrome N Engl J Med 333 853-861
  • [2] Goodarzi MO(2011)Polycystic ovary syndrome: etiology, pathogenesis and diagnosis Nat Rev Endocrinol 7 219-231
  • [3] Dumesic DA(1935)Amenorrhoea associated with bilateral polycystic ovaries Am J Obstet Gynecol 29 181-191
  • [4] Chazenbalk G(1980)Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease J Clin Endocrinol Metab 50 113-116
  • [5] Azziz R(2006)Controversy in clinical endocrinology: diagnosis of polycystic ovarian syndrome: in defense of the Rotterdam criteria J Clin Endocrinol Metab 91 786-789
  • [6] Stein IF(2006)Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline J Clin Endocrinol Metab 91 4237-4245
  • [7] Leventhal ML(2011)Treatment options for polycystic ovary syndrome Int J Womens Health 3 25-35
  • [8] Burghen GA(2011)Laparoscopic ovarian drilling for clomiphene-resistant polycystic ovary syndrome Semin Reprod Med 29 138-146
  • [9] Givens JR(2011)Ovarian drilling for surgical treatment of polycystic ovarian syndrome: a comprehensive review Reprod Biomed Online 22 556-568
  • [10] Kitabchi AE(2011)Prospective, randomized comparison between raloxifene and clomiphene citrate for ovulation induction in polycystic ovary syndrome Fertil Steril 96 769-773
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