State and Recent Progress of Nuclear Cardiology in China

被引：0
|
作者：
Zhang X. [1 ]
Yang Y. [1 ]
Wei H. [1 ]
Tian Y. [1 ]
Shi H. [4 ]
Wang Y. [3 ]
Li S. [2 ]
He Z.-X. [1 ]
Li Y. [5 ]
Liu X.-J. [1 ]
机构：
[1] Department of Nuclear Medicine, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing
[2] Department of Nuclear Medicine, The First Hospital of Shanxi Medical University, 85 Jie Fang Sth Road, Taiyuan, 030001, Shanxi
[3] Department of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou
[4] Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai
[5] Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang
来源：
Current Cardiovascular Imaging Reports | 2015年 / 8卷 / 5期
基金：
中国国家自然科学基金;
关键词：
Adenosine; Aneurysm; Coronary angiography; Coronary disease; Higenamine hydrochloride; Myocardial infarction; Myocardial ischemia; Myocardial viability; Phase analysis; Prognosis; Remodeling; Sestamibi; Tomography; emission-computed; Ventricular function; left;
D O I：
10.1007/s12410-015-9332-2
中图分类号：
学科分类号：
摘要：
In this review, we focus mainly on the clinical applications of myocardial perfusion imaging (MPI) with single-photon emission CT (SPECT) and metabolic imaging in clinical practice. Important advances have been made in the clinical applications of MPI, including its role in stratifying risk and guiding management decisions. The impact of incomplete and complete myocardial ischemia correction on long-term outcomes was analyzed and compared with complete and incomplete diseased vessel intervention. Importantly, a new pharmacologic stress testing agent—higenamine—was developed and has completed phase III clinical trials. Ventricular synchrony was assessed by phase analysis of gated MPI in healthy Chinese subjects and in patients with or without left ventricular (LV) dysfunction. Finally, the clinical value of technetium (99mTc) sestamibi SPECT and fludeoxyglucose (18F-FDG) positron emission tomography (PET) in patients with LV aneurysms was deeply investigated. Viability of LV aneurysm in patients with ischemic cardiomyopathy was a negative independent predictor of survival. The diagnostic accuracy of LV parameters analyzed by both gated SPECT and gated PET was investigated in patients with LV aneurysm, who revealed severe perfusion defects and LV remodeling. Additionally, end-systolic volume measured by gated PET was the only independent predictor of cardiac death among all the LV functional parameters evaluated by gated SPECT, gated PET, cardiac magnetic resonance imaging, and echocardiography. © 2015, Springer Science+Business Media New York.
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页码：1 / 10
页数：9
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