Naproxen: Hydroxypropyl-β-Cyclodextrin:Polyvinylpyrrolidone Ternary Complex Formation

被引：0
作者：
Margarita Valero
Brígida Esteban
Rafael Peläez
Licesio J. Rodrïguez
机构：
[1] Universidad de Salamanca,Departamento de Química Física, Facultad de Farmacia
来源：
Journal of inclusion phenomena and macrocyclic chemistry | 2004年 / 48卷
关键词：
naproxen; hydroxypropyl-β-cyclodextrin; polyvinylpyrrolidone; ternary complex;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The aim of the present study was to investigate the effect of the presence of thewater-soluble polymer polyvinylpyrrolidone (PVP) MW = 24000 g/mol, on thecomplexation of the phototoxic anti-inflammatory drug naproxen, in its sodiumsalt form, with hydroxypropil-β-cyclodextrin (HP-β-CD). The datashown that the polymer interacts with the free naproxen and with thenaproxen:HP-β-CD inclusion complex.
引用
收藏
页码：157 / 163
页数：6
相关论文
共 86 条
  • [1] Moore D.E.(1988)undefined Photochem. Photobiol. 47 173-undefined
  • [2] Chappuis P.P.(1988)undefined J. Photochem. Photobiol. B: Biol. 43 1-undefined
  • [3] Boscá F.(2001)undefined Eur. J. Pharm. Sci. 13 187-undefined
  • [4] Miranda M.A.(2001)undefined J. Photochem. Photobiol. A: Chem. 140 67-undefined
  • [5] Mura P.(1988)undefined Int. J. Pharm. 48 83-undefined
  • [6] Faucci M.T.(1988)undefined Pharmazie 53 11-undefined
  • [7] Bettinetti G.P.(1997)undefined Pharm. Tech. Eur. 9 26-undefined
  • [8] Partyka M.(1994)undefined Pharmazie 49 497-undefined
  • [9] Ha Au B.(1995)undefined Int. J. Pharm. 126 73-undefined
  • [10] Evans C.H.(1994)undefined Drug Dev. Ind. Pharm. 20 1353-undefined
123456789