Reduced hypertrophy in vitro after chondrogenic differentiation of adult human mesenchymal stem cells following adenoviral SOX9 gene delivery

被引：0
|
作者：
M. Weissenberger
M. H. Weissenberger
F. Gilbert
J. Groll
C. H. Evans
A. F. Steinert
机构：
[1] Julius-Maximilians-University,Department of Orthopaedic Surgery, König
[2] Caritas-Hospital,Ludwig
[3] University Hospital Würzburg,Haus, Center for Musculoskeletal Research
[4] Julius-Maximilians-University,Department of Pathology
[5] Mayo Clinic,Department of Orthopaedic Trauma, Hand, Plastic and Reconstructive Surgery
[6] Rhön-Klinikum Campus Bad Neustadt,Department of Functional Materials in Medicine and Dentistry
来源：
BMC Musculoskeletal Disorders | / 21卷
关键词：
Mesenchymal stem cell; Cartilage; SOX9; Gene therapy; Chondrogenesis; Hypertrophy; Adenovirus; Bone marrow;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Reduced hypertrophy in vitro after chondrogenic differentiation of adult human mesenchymal stem cells following adenoviral SOX9 gene delivery
    Weissenberger, M.
    Weissenberger, M. H.
    Gilbert, F.
    Groll, J.
    Evans, C. H.
    Steinert, A. F.
    BMC MUSCULOSKELETAL DISORDERS, 2020, 21 (01)
  • [2] Chondrogenic Differentiation of Human Mesenchymal Stem Cells via SOX9 Delivery in Cationic Niosomes
    Carballo-Pedrares, Natalia
    Sanjurjo-Rodriguez, Clara
    Senaris, Jose
    Diaz-Prado, Silvia
    Rey-Rico, Ana
    PHARMACEUTICS, 2022, 14 (11)
  • [3] Delivery of the Sox9 gene promotes chondrogenic differentiation of human umbilical cord blood-derived mesenchymal stem cells in an in vitro model
    Wang, Z. H.
    Li, X. L.
    He, X. J.
    Wu, B. J.
    Xu, M.
    Chang, H. M.
    Zhang, X. H.
    Xing, Z.
    Jing, X. H.
    Kong, D. M.
    Kou, X. H.
    Yang, Y. Y.
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2014, 47 (04) : 279 - 286
  • [4] KLF15 regulates in vitro chondrogenic differentiation of human mesenchymal stem cells by targeting SOX9
    Song, Zhuoyue
    Lian, Xiaolei
    Wang, Yang
    Xiang, Yong
    Li, Guangheng
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 493 (02) : 1082 - 1088
  • [5] microRNA-495 Inhibits Chondrogenic Differentiation in Human Mesenchymal Stem Cells by Targeting Sox9
    Lee, Seulgi
    Yoon, Dong Suk
    Paik, Seungil
    Lee, Kyoung-Mi
    Jang, Yeonsue
    Lee, Jin Woo
    STEM CELLS AND DEVELOPMENT, 2014, 23 (15) : 1798 - 1808
  • [6] MicroRNA-145 Regulates Chondrogenic Differentiation of Mesenchymal Stem Cells by Targeting Sox9
    Yang, Bo
    Guo, Hongfeng
    Zhang, Yulan
    Chen, Lei
    Ying, Dajun
    Dong, Shiwu
    PLOS ONE, 2011, 6 (07):
  • [7] INHIBITORY EFFECTS OF IL-17 ON CHONDROGENIC DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS THROUGH THE PHOSPHORYLATION OF SOX9
    Kondo, M.
    Yamaoka, K.
    Sonomoto, K.
    Fukuyo, S.
    Oshita, K.
    Okada, Y.
    Saito, K.
    Tanaka, Y.
    ANNALS OF THE RHEUMATIC DISEASES, 2013, 72 : 158 - 158
  • [8] IN VITRO GENE KNOCKDOWN OF SOX9 AFFECTS CELL SURVIVAL AND OSTEOGENIC DIFFERENTIATION OF MESENCHYMAL STEM CELLS
    Stockl, S.
    Gottl, C.
    Grifka, J.
    Grassel, S.
    OSTEOARTHRITIS AND CARTILAGE, 2010, 18 : S233 - S233
  • [9] Perlecan is required for the chondrogenic differentiation of synovial mesenchymal cells through regulation of Sox9 gene expression
    Sadatsuki, Ryo
    Kaneko, Haruka
    Kinoshita, Mayuko
    Futami, Ippei
    Nonaka, Risa
    Culley, Kirsty L.
    Otero, Miguel
    Hada, Shinnosuke
    Goldring, Mary B.
    Yamada, Yoshihiko
    Kaneko, Kazuo
    Arikawa-Hirasawa, Eri
    Ishijima, Muneaki
    JOURNAL OF ORTHOPAEDIC RESEARCH, 2017, 35 (04) : 837 - 846
  • [10] The long non-coding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells
    Barter, Matt J.
    Gomez, Rodolfo
    Hyatt, Sam
    Cheung, Kat
    Skelton, Andrew J.
    Xu, Yaobo
    Clark, Ian M.
    Young, David A.
    DEVELOPMENT, 2017, 144 (24): : 4510 - 4521
12345