Bevacizumab and irinotecan treatment for progressive diffuse brainstem glioma: case report

被引:0
作者
Roy Torcuator
Richard Zuniga
Randa Loutfi
Tom Mikkelsen
机构
[1] Henry Ford Health System,Department of Neurosurgery
[2] Hermelin Brain Tumor Center,Henry Ford Health System
[3] Hermelin Brain Tumor Center,Department of Medical Oncology
[4] Henry Ford Health System,Department of Neurology
[5] Hermelin Brain Tumor Center,undefined
[6] Henry Ford Health System,undefined
[7] Hermelin Brain Tumor Center,undefined
来源
Journal of Neuro-Oncology | 2009年 / 93卷
关键词
Brainstem; Glioma; Diffuse chemotherapy; Bevacizumab; Irinotecan;
D O I
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中图分类号
学科分类号
摘要
Diffuse brainstem glioma carries a dismal prognosis. The current cornerstone of treatment is radiation therapy. Chemotherapy appears to be ineffective and the role of this treatment in the recurrent or progressive setting is not known. Bevacizumab and irinotecan have been reported to have shown radiographic response and improvement in progression-free survival among patients with malignant supratentorial gliomas. In this paper, we report our experience in an adult patient with progressive diffuse brainstem glioma treated with bevacizumab and irinotecan.
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页码:409 / 412
页数:3
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  • [1] Packer RJ(1999)Brain tumors in children Arch Neurol 56 421-425
  • [2] Freeman CR(1998)Pediatric brain stem gliomas: a review Int J Radiat Oncol Biol Phys 40 265-271
  • [3] Farmer JP(1998)Pediatric brain stem gliomas: an update Childs Nerv Syst 14 167-173
  • [4] Rubin G(2001)Brainstem gliomas in adults: prognostic factors and classification Brain 124 2528-2539
  • [5] Michowitz S(2008)Diffuse pontine gliomas in children: changing strategies, changing results? A mono-institutional 20-year experience J Neurooncol 87 355-361
  • [6] Horev G(1998)Adult brainstem gliomas Neurology 51 1136-1139
  • [7] Herscovici Z(1999)Brainstem glioma: comparative study of clinico-radiological presentation, pathology and outcome in children and adults Acta Neurochir (Wien) 141 721-726
  • [8] Cohen IJ(1996)Practical decisions in the treatment of pediatric brain stem tumors Pediatr Neurosurg 24 24-34
  • [9] Shuper A(1998)The results of radiotherapy for brainstem tumors J Neurooncol 40 171-177
  • [10] Rappaport ZH(1999)Chemotherapy for brain stem gliomas Childs Nerv Syst 15 545-553