Dengue and Other Viral Hemorrhagic Fevers in India

被引：0
作者：
Shally Awasthi
U. C. Chaturvedi
机构：
[1] CSM Medical University,Department of Pediatrics
来源：
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences | 2012年 / 82卷
关键词：
Hemorrhagic fevers; Dengue; Kyasanur forest disease; Virion; Hantaviruses;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The important viral hemorrhagic fevers (VHF) in India spread by an arthropod vectors are Dengue fever/Dengue haemorrhagic fever and Kyasanur forest disease. Another VHF is caused by Hanta virus infection and for this there is no known vector. The diagnosis of VHF is based on typical clinical presentation and thereafter confirmed by detection of either virus or viral RNA or by demonstration of a rise of antibody titres against it. Treatment is by and large symptomatic as there are no specific drugs available against the viruses. Dengue fever has acquired epidemic magnitude in certain parts of India and has about 10% mortality. Research is going on for the development of effective vaccines against Dengue fever. The principles of primary prevention of vector borne diseases is through vector control measures, elimination of breeding sites in and around human dwellings and personal protection against vector bite.
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页码：69 / 80
页数：11
相关论文
共 137 条
  • [1] Mehla R(2009)Recent ancestry of Kyasanur forest disease virus Emerg Infect Dis 15 1431-1437
  • [2] Kumar SR(2007)Prospects for a dengue virus vaccine Nat Rev Microbiol 5 518-528
  • [3] Yadav P(1974)Etiologies of the experimental dengues of Siler and Simmons Am J Trop Med Hyg 23 974-982
  • [4] Barde PV(1970)Observations related to pathogenesis of dengue hemorrhagic fever Yale J Biol Med 42 311-328
  • [5] Yergolkar PN(1984)Risk factors in dengue shock syndrome: a prospective epidemiologic study in Rayong, Thailand. I. The 1980 out break Am J Epidemiol 120 653-669
  • [6] Erickson BR(2000)Epidemiologic studies on dengue in Santiago de Cuba, 1997 Am J Epidemiol 152 793-799
  • [7] Whitehead SS(1989)Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade Rev Infect Dis 11 830-839
  • [8] Blaney JE(2005)Dengue virus: molecular basis of cell entry and pathogenesis, 25–27 June 2003, Vienna, Austria Vaccine 23 849-856
  • [9] Durbin AP(2008)Vascular endothelium: the battle field of dengue viruses FEMS Immunol Med Microbiol 53 287-299
  • [10] Murphy BR(2000)Cytokine cascade in dengue haemorrhagic fever: implications for pathogenesis FEMS Immunol Med Microbiol 28 183-188
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