Comparative evaluation of Point Of Care coagulation monitoring by coaguchek XS-comparison with standard laboratory method

被引：6

作者：

Lakshmy R. ^{[1
,2
]}

Kumar A.S. ^{[1
]}

机构：

[1] Cardiothoracic Center, All India Institute of Medical Sciences, New Delhi

[2] Department of Cardiac Biochemistry, All India Institute of Medical Sciences, New Delhi

来源：

Indian Journal of Thoracic and Cardiovascular Surgery | 2010年 / 26卷 / 2期

关键词：

Coaguchek XS; Correlation; POC monitors; PT/INR;

D O I：

10.1007/s12055-010-0028-6

中图分类号：

学科分类号：

摘要：

Background: Point Of Care (POC) meters are a relatively less invasive and rapid method for monitoring of Prothrombin Time/Interational Normalized Ratio (PT/INR) in patients on anticoagulant therapy. The reliability of results obtained with meters, however, needs to be affirmed and their accuracy needs to be assessed by comparing with standard laboratory analysis. We assessed the Coaguchek XS (Roche) PT/INR meter for accuracy and reliability by comparing with the results obtained with standard laboratory analysis on Stago Coagulometer. Methods: INR values of 42 patients were measured by standard laboratory method using thromboplastin, Neoplastin CI (Diagnostical Stago, France) with ISI of 1. 7 on Coagulometer (Stago) in plasma. Simultaneously a drop of blood was taken on the strip for Coagulochek XS and the INR read by the meter. Correlation between INR values obtained by the two methods was assessed by computing the correlation coefficient and the intra class correlation coefficient. Agreement between the INR values was assessed by Bland Altman plots. Results: An excellent correlation was observed between INR values obtained by coaguchek XS and the values obtained in the laboratory by standard method for a range of values. Bland Altman plots showed good agreement between values obtained by the two methods with only three values falling beyond 2SD limits. Conclusion: In conclusion Coaguchek XS INR meters are reliable and accurate and can be used by patients for monitoring of anticoagulation therapy. © 2010 Indian Association of Cardiovascular-Thoracic Surgeons.

引用

页码：125 / 128

页数：3

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