Induced psoriasis after rituximab therapy for rheumatoid arthritis: a case report and review of the literature

被引：0
作者：
G. M. Guidelli
A. Fioravanti
P. Rubegni
L. Feci
机构：
[1] Siena University,Rheumatology Unit, Department of Clinical Medicine and Immunology
[2] Siena University,Dermatology section, Department of Clinical Medicine and Immunology
来源：
Rheumatology International | 2013年 / 33卷
关键词：
Psoriasis; Rituximab; Rheumatoid arthritis; Adverse events;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Rituximab is a human/murine monoclonal antibody targeting the CD20 antigen on B-lymphocytes surface. Although it has been licensed for treatment of non-Hodgkin’s lymphoma, nowadays it is also a novel therapy for autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. Despite the increasing evidence regarding the safety and efficacy of rituximab in these conditions, many cutaneous adverse events have been reported. Here, we describe the case of a 69-year-old patient, affected by rheumatoid arthritis, who developed psoriatic lesions on her trunk and arms, three months after the second course of rituximab. Similar cases appearing in the literature will also be briefly mentioned.
引用
收藏
页码：2927 / 2930
页数：3
相关论文
共 53 条
[1]  
Emery P(2006)The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial Arthr Rheum 54 1390-1400
[2]  
Fleischmann R(2011)The efficacy and safety of rutuximab for the treatment of active rheumatoid arthritis: a systematic review and meta-analysis of randomized controlled trials Rheumatol Int 31 1493-1499
[3]  
Filipowicz-Sosnowska A(2002)Stevens–johnson syndrome after treatment with rituximab Ann Oncol 13 1948-1950
[4]  
Schechtman J(2009)Induction of psoriatic skin lesions in a patient with rheumatoid arthritis treated with rituximab Clin Exp Rheumatol 27 996-998
[5]  
Szczepanski L(2007)Development of psoriasis after B cell depletion with rituximab Arthr Rheum 56 2715-2718
[6]  
Kavanaugh A(2008)Onset of psoriasis with psoriatic arthropathy during rituximab treatment of non-Hodgkin lymphoma Ann Rheum Dis 67 1056-1057
[7]  
Lee YH(2001)Rituximab: mechanisms and applications Br J Cancer 85 1619-1623
[8]  
Bae SC(1999)Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte counts after treatment with an anti-CD20 monoclonal antibody (rituximab, IDEC-C2B8) Blood 94 2217-2224
[9]  
Song GG(2001)Serum sickness secondary to treatment with the murine-human chimeric antibody IDEC-C2B8 (rituximab) Arthr Rheum 44 1717-1718
[10]  
Lowndes S(2002)Rituximab-induced serum sickness Am J Hematol 70 329-84
123456