Free Radical Scavenging Activity of Aqueous and Ethanolic Extract of Brassica oleracea L. var. italica

被引：0
作者：
Abdul Mueed Bidchol
A. Wilfred
P. Abhijna
R. Harish
机构：
[1] Pooja Bhagavat Memorial Mahajana Post Graduate Center,Department of Studies in Biotechnology
[2] Wing of SBRR Mahajana Education Centre,undefined
来源：
Food and Bioprocess Technology | 2011年 / 4卷
关键词：
L. var. ; Antioxidant activity; Reactive oxygen species; Lipid peroxidation; Metal ion chelation;
D O I：
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学科分类号：
摘要：
In this study, antioxidant activities of aqueous and ethanolic extracts of Brassica oleracea L. var. italica were investigated. The antioxidant properties of both extracts of Brassica oleracea L. var. italica were evaluated using different antioxidant tests, including 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, superoxide radical scavenging, inhibition of microsomal lipid peroxidation, reduction of power, and metal ion chelating activities. Inhibition of superoxide scavenging by aqueous and ethanolic extracts showed an IC50 of 0.93 and 0.25 mg/ml, respectively. Metal ion chelation showed an IC50 of 0.35 mg/ml of both the extracts and was equipotent to positive control, ethylenediamine tetra-acetic acid. The ethanolic extract of Brassica oleracea L. var. italica exhibited higher antioxidant activity in DPPH radical and superoxide anion scavenging than that of aqueous extract. The results obtained in the in vitro models clearly suggest that, Brassica oleracea L. var. italica is a natural source for antioxidants, which could serve as a nutraceutical with potential applications in reducing the level of oxidative stress and related health benefits. However, comprehensive studies need to be conducted to ascertain the in vivo safety of such extracts in experimental animal models.
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页码：1137 / 1143
页数：6
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