Nutritional Supplementation for Patients with Decompensated Cirrhosis

被引:1
作者
Vidot H. [1 ]
Shackel N.A. [2 ]
机构
[1] Department Nutrition and Dietetics, Royal Prince Alfred Hospital, Camperdown, 2050, NSW
[2] The Anzac Research Institute, Hospital Road, Concord, 2139, NSW
关键词
Decompensated cirrhosis; Hepatic encephalopathy; Malnutrition; Muscle cramps; Muscle wasting;
D O I
10.1007/s11901-021-00561-1
中图分类号
学科分类号
摘要
Purpose of Review: Malnutrition is common in patients with decompensated cirrhosis and portal hypertension and is associated with impaired health-related quality of life and reduced survival. This review aims to explore the outcomes of specific nutritional interventions in the management of malnourished patients with decompensated cirrhosis. Recent Findings: Nutritional assessment and intervention is an important adjunct in the management of decompensated cirrhosis. Nutrition support in patients with decompensated cirrhosis can preserve muscle mass and alleviate the manifestations of decompensation including ascites, hepatic encephalopathy and muscle cramps. Summary: Addressing nutritional deficiencies in cirrhosis is integral to the care of these patients. Current nutritional management strategies and targeted supplementation in decompensated cirrhosis can improve symptoms of decompensation and quality of life as well as improve patient survival. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021.
引用
收藏
页码:53 / 60
页数:7
相关论文
共 68 条
[1]  
Van den Burghe G., The role of the liver in metabolic homeostasis: implications for inborn errors of metabolism, J lnherit Metab Dis, 14, pp. 407-420, (1991)
[2]  
Saunders J., Brian A., Wright M., Stroud M., Malnutrition and nutrition support in patients with liver disease, Frontline Gastroenterol, 1, pp. 105-111, (2010)
[3]  
Lautz H.U., Selberg O., Korber J., Burger M., Muller M.J., Protein-calorie malnutrition in liver cirrhosis, Clin Investig, 70, pp. 478-486, (1992)
[4]  
Merli M., Nutrition in cirrhosis: dos and don’ts, J Hepatol, S0168-8278, pp. 30474-30478, (2020)
[5]  
Chang W.K., Chao Y.C., Tang H.S., Lang H.F., Hsu C.T., Effects of extra-carbohydrate supplementation in the late evening on energy expenditure and substrate oxidation in patients with liver cirrhosis, JPEN J Parenter Enteral Nutr, 21, pp. 96-99, (1997)
[6]  
Anand A.C., Nutrition and Muscle in Cirrhosis, J Clin Exp Hepatol, 7, pp. 340-357, (2017)
[7]  
Konig M., Bulik S., Holzhutter H.-G., Quantifying the contribution of the liver to glucose homeostasis: a detailed kinetic model of human hepatic glucose metabolism, PLoS Comput Biol, 8, (2012)
[8]  
Adeva-Andany M.M., Perez-Felpete N., Fernandez-Fernandez C., Donapetry-Garcia C., Pazos-Garcia C., Liver glucose metabolism in humans, Biosci Rep, 36, (2016)
[9]  
Krahenbuhl L., Lang C., Ludes S., Seiler C., Reduced hepatic glycogen stores in patients with liver cirrhosis, Liver Int, 23, pp. 101-109, (2003)
[10]  
Plauth M., Merli M., Kondrup J., Weimann A., Ferenci P., Muller M.J., ESPEN guidelines for nutrition in liver disease and transplantation, Clin Nutr, 16, pp. 43-55, (1997)