Synchronous gastric adenocarcinoma and gastrointestinal stromal tumor (GIST) of the stomach: A case report

被引：0
作者：
Theodosios Theodosopoulos
Dionysios Dellaportas
Vasiliki Psychogiou
Konstantinos Gennatas
Agathi Kondi-Pafiti
Georgios Gkiokas
Ioannis Papaconstantinou
Georgios Polymeneas
机构：
[1] University Hospital Aretaieion,2nd Department of Surgery
[2] University Hospital Aretaieion,1st Department of Pathology
[3] University Hospital Aretaieion,Department of Oncology
来源：
World Journal of Surgical Oncology | / 9卷
关键词：
gastric adenocarcinoma; gastrointestinal stromal tumor (GIST);
D O I：
暂无
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学科分类号：
摘要：
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms of the gastrointestinal tract (1%), and stomach is the most common location involved. However, the co-existence of gastric adenocarcinoma and GIST is very rare. A case of an 80-year-old male with a simultaneous presentation of a gastric adenocarcinoma and GIST is presented. Various hypotheses have been proposed in order to explain this rare simultaneous development, but even though it's cause has not been proven yet.
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[1]  
Miettinen A(2006)Gastrointestinal stromal tumors: pathology and prognosis at different sites Semin Diagn Pathol 23 70-83
[2]  
Nowain H(2005)Gastrointestinal stromal tumors: clinical profile, pathogenesis, treatment strategies and prognosis J Gastroenterol Hepatol 20 818-824
[3]  
Bhakta S(2005)Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era--a population-based study in western Sweden Cancer 103 821-829
[4]  
Pais G(1998)Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal Am J Pathol 152 1259-1269
[5]  
Kanel S(2003)Expression and mutation of c-kit gene in gastrointestinal stromal tumors World J Gastroenterol 9 2548-2551
[6]  
Verma A(1983)Gastric stromal tumors. Reappraisal of histogenesis Am J Surg Pathol 7 507-519
[7]  
Dortok B(2003)Expression and mutation of c-kit gene in gastrointestinal stromal tumors World J Gastroenterol 9 2548-2551
[8]  
Gustavsson K(2002)Diagnosis of gastrointestinal stromal tumors: A consensus approach Hum Pathol 33 459-465
[9]  
Sablinska LG(2000)Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors J Pharmacol Exp Ther 295 139-145
[10]  
Kindblom LG(2000)Synchronous occurrence of epithelial and stromal tumors in the stomach: a report of 6 cases Arch Pathol Lab Med 124 682-686
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