CXCL1-LCN2 paracrine axis promotes progression of prostate cancer via the Src activation and epithelial-mesenchymal transition

被引:0
作者
Yongning Lu
Baijun Dong
Fan Xu
Yunze Xu
Jiahua Pan
Jiajia Song
Jin Zhang
Yiran Huang
Wei Xue
机构
[1] Shanghai Jiao Tong University,Department of Urology, Renji Hospital, School of Medicine
[2] Fudan University,Reproductive Medicine Centre, Zhongshan Hospital
来源
Cell Communication and Signaling | / 17卷
关键词
Chemokine; Cytokine; Tumor cell migration; Tumor metastasis; Tumor microenvironment;
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暂无
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[1]  
Jemal A(2008)Cancer statistics, 2008 CA Cancer J Clin 58 71-96
[2]  
Siegel R(2012)Clinical development of novel therapeutics for castration-resistant prostate cancer: historic challenges and recent successes CA Cancer J Clin 62 299-308
[3]  
Ward E(2016)Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence Endocr Relat Cancer 23 T179-T197
[4]  
Hao Y(2017)Stromal factors involved in human prostate cancer development, progression and castration resistance J Cancer Res Clin Oncol 143 351-359
[5]  
Xu J(2008)Stromal myofibroblasts are drivers of invasive cancer growth Int J Cancer 123 2229-2238
[6]  
Murray T(2005)Nonapical and cytoplasmic expression of interleukin-8, CXCR1, and CXCR2 correlates with cell proliferation and microvessel density in prostate cancer Clin Cancer Res 11 4117-4127
[7]  
Thun MJ(2010)Role of chemokines and chemokine receptors in prostate Cancer development and progression J Cancer Sci Ther 2 89-94
[8]  
Galsky MD(2014)Chemokine (C-X-C motif) ligand 1 (CXCL1) protein expression is increased in high-grade prostate cancer Pathol Res Pract 210 74-78
[9]  
Small AC(2015)Secretome analysis of an osteogenic prostate tumor identifies complex signaling networks mediating cross-talk of cancer and stromal cells within the tumor microenvironment Mol Cell Proteomics 14 471-483
[10]  
Tsao CK(2016)CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment Nat Commun 7 11674-1802