Pulsed Dendritic Cells for the Therapy of Experimental Glioma

被引：0

作者：

I. V. Chekhonin

O. I. Gurina

S. A. Cherepanov

M. A. Abakumov

K. P. Ionova

D. K. Zhigarev

A. V. Makarov

V. P. Chekhonin

机构：

[1] Ministry of Health of the Russian Federation,V. P. Serbsky Federal Medical Research Centre of Psychiatry and Narcology

[2] N. I. Pirogov Russian National Research Medical University,Department of Medical Nanobiotechnologies, Medical Biological Faculty

[3] Ministry of Health of the Russian Federation,undefined

来源：

Bulletin of Experimental Biology and Medicine | 2016年 / 161卷

关键词：

dendritic cells; glioma; neurospecific proteins; angiogenesis; periglioma zone;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

We obtained the morphologically, cytofluorometrically, and functionally mature dendritic cells from rats that were pulsed with antigens of the C6 glioma tissue extract. The concentrations of angiogenesis antigens (VEGF, VEGFR-1, and VEGFR-2) and periglioma zone proteins (GFAP, connexin 43, and BSAT1) in the pulsing extract were measured by ELISA. Our results drove us to a conclusion that despite mature phenotype of pulsed dendritic cell, the antigenic composition of glioma tissue extracts should be modified.

引用

页码：792 / 796

页数：4

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