Analgesic effect of corticotropin-releasing hormone: Involvement of the hypothalamic-pituitary-adrenocortical axis into its realization

被引：0

作者：

A. I. Bogdanov

N. I. Yarushkina

机构：

[1] Russian Academy of Sciences,Laboratory of Experimental Endocrinology, I. P. Pavlov Institute of Physiology

来源：

Bulletin of Experimental Biology and Medicine | 2006年 / 141卷

关键词：

corticotropin-releasing hormone; nociception; corticosterone; opioid receptor; rat;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Involvement of hypothalamic-pituitary-adrenocortical axis into the analgesic effect of corticotropin-releasing hormone after its systemic administration was studied in experiments on rats. Pharmacological blockade of the hypothalamic-pituitary-adrenocortical axis decreased the duration and degree of the analgesic effect of corticotropin-releasing hormone. This analgesic effect can be mediated via two pathways: related to hormones of the hypothalamic-pituitary-adrenocortical axis and independent of these hormones.

引用

页码：184 / 186

页数：2

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