Diagnosis and Management of Subcutaneous Soft Tissue Sarcoma

被引:0
作者
Makoto Endo
Nokitaka Setsu
Toshifumi Fujiwara
Takeaki Ishii
Makoto Nakagawa
Kenichiro Yahiro
Atsushi Kimura
Eijiro Shimada
Yasuharu Nakashima
Yoshihiro Matsumoto
机构
[1] Kyushu University,Department of Orthopaedic Surgery
来源
Current Treatment Options in Oncology | 2019年 / 20卷
关键词
Sarcoma; Soft tissue sarcoma; Soft tissue tumor; Superficial soft tissue sarcoma; Subcutaneous soft tissue sarcoma; Subcutaneous soft tissue tumor;
D O I
暂无
中图分类号
学科分类号
摘要
The proper diagnosis and treatment planning for subcutaneous soft tissue sarcoma is very important. Soft tissue tumors can occur anywhere in the body, but if they occur subcutaneously, patients can easily notice a subcutaneous soft tissue mass. Therefore, it is possible to determine through recording, the growth speed of the mass, which is often difficult to obtain with deep-situated soft tissue masses. Palpation can also provide information about the firmness and mobility of the mass. Thus, history taking and physical examinations are informative for subcutaneous soft tissue tumors, compared to tumors that occur deeply. Because subcutaneous soft tissue tumors are easily recognized, they are often resected, without sufficient imaging analyses or thorough treatment planning. An operation performed based on such an inadequate preoperative plan is called a “whoops surgery.” In the case of “whoops surgeries,” subsequent radical surgery is required to remove additional areas, including hematomas that result from the initial surgery, that require a wider range of resection and soft tissue reconstruction. Therefore, as with deep-seated soft tissue tumors, it is important to conduct careful imaging examinations and make appropriate preoperative plans for subcutaneous soft tissue tumors. Subcutaneous soft tissue sarcomas often show an invasive pattern, and such tumors require a more careful assessment to prevent local recurrence after surgery. During surgery, it is necessary to remove the entire infiltration area along the fascia. Sometimes, an adequately wide excision is necessary, which is considered the minimum necessary procedure to eradicate the lesion. As noted above, clinicians who see patients with subcutaneous soft tissue tumors are encouraged to have sufficient knowledge and experience regarding the diagnosis and treatment. This article is intended for all doctors who deal with subcutaneous soft tissue tumors and focuses on essential points regarding their diagnosis and management.
引用
收藏
相关论文
共 489 条
[1]  
Rydholm A(1991)Subcutaneous sarcoma. A population-based study of 129 patients J Bone Joint Surg (Br) 73 662-667
[2]  
Gustafson P(2015)Unplanned excision of soft-tissue sarcomas: current concepts for management and prognosis J Bone Joint Surg Am 97 597-603
[3]  
Rooser B(2017)Diagnosis and treatment of soft-tissue sarcomas of the extremities and trunk EFORT Open Rev 2 421-431
[4]  
Willen H(2009)Ethanol sclerotherapy reduces pain in symptomatic musculoskeletal hemangiomas Clin Orthop Relat Res 467 2955-2961
[5]  
Berg NO(2013)Prognostic impact of the activation status of the Akt/mTOR pathway in synovial sarcoma Cancer. 119 3504-3513
[6]  
Pretell-Mazzini J(2013)Conventional spindle cell-type malignant peripheral nerve sheath tumor arising in a sporadic schwannoma Hum Pathol 44 2845-2848
[7]  
Barton MD(2011)Prognostic significance of p14ARF, p15INK4b, and p16INK4a inactivation in malignant peripheral nerve sheath tumors Clin Cancer Res 17 3771-3782
[8]  
Conway SA(2013)Prognostic significance of AKT/mTOR and MAPK pathways and antitumor effect of mTOR inhibitor in NF1-related and sporadic malignant peripheral nerve sheath tumors Clin Cancer Res 19 450-461
[9]  
Temple HT(2014)CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies Am J Med Genet A 164A 563-578
[10]  
Smolle MA(2018)Management of soft tissue tumors of the musculoskeletal system Orthop Traumatol Surg Res 104 S9-S17