The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

被引：0
|
作者：
Mark R. Cookson
机构：
[1] Mark R. Cookson is at the Laboratory of Neurogenetics,
[2] National Institute on Aging,undefined
[3] National Institutes of Health (NIH),undefined
[4] Building 35,undefined
[5] Room 1A116,undefined
[6] MSC 3707,undefined
[7] 35 Convent Drive,undefined
[8] Bethesda,undefined
[9] Maryland 20982-3707,undefined
[10] USA. Cookson@mail.nih.gov,undefined
来源：
Nature Reviews Neuroscience | 2010年 / 11卷
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摘要：
Recent evidence suggests that mutations inLRRK2are linked to Parkinson's disease. In this Progress article, Mark Cookson discusses how these mutations might affect LRRK2 function and its interactions with other proteins that have been implicated in Parkinson's disease, specifically α-synuclein and tau.
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页码：791 / 797
页数：6
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