Selection plays the hand it was dealt: evidence that human adaptation commonly targets standing genetic variation

被引：0

作者：

Rajiv C. McCoy

Joshua M. Akey

机构：

[1] University of Washington,Department of Genome Sciences

来源：

Genome Biology | / 18卷

关键词：

Recent Positive Selection; Soft Selective Sweeps; Schridde; Hard Sweep; Human Evolutionary Biology;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Using a powerful machine learning approach, a recent study of human genomes has revealed widespread footprints of recent positive selection on standing genetic variation.

引用

共 4 条

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Gomez, Felicia
Hirbo, Jibril
Tishkoff, Sarah A.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2014, 6 (07):
[2] Population genetic analysis of the DARC locus (Duffy) reveals adaptation from standing variation associated with malaria resistance in humans
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PLOS GENETICS, 2017, 13 (03):
[3] Genetic Variation in Human Gene Regulatory Factors Uncovers Regulatory Roles in Local Adaptation and Disease
Perdomo-Sabogal, Alvaro
Nowick, Katja
GENOME BIOLOGY AND EVOLUTION, 2019, 11 (08): : 2178 - 2193
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Lohmueller, Kirk E.
Albrechtsen, Anders
Li, Yingrui
Kim, Su Yeon
Korneliussen, Thorfinn
Vinckenbosch, Nicolas
Tian, Geng
Huerta-Sanchez, Emilia
Feder, Alison F.
Grarup, Niels
Jorgensen, Torben
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Witte, Daniel R.
Sandbaek, Annelli
Hellmann, Ines
Lauritzen, Torsten
Hansen, Torben
Pedersen, Oluf
Wang, Jun
Nielsen, Rasmus
PLOS GENETICS, 2011, 7 (10):

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