CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity

被引：0
|
作者：
Manu Sharma
Jacqueline Burré
Thomas C. Südhof
机构：
[1] Stanford University,Department of Molecular and Cellular Physiology
[2] Howard Hughes Medical Institute,undefined
[3] Stanford University,undefined
来源：
Nature Cell Biology | 2011年 / 13卷
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摘要：
A chaperone complex containing CSPα, Hsc70 and SGT binds to monomeric SNAP-25 and prevents its aggregation and degradation. Loss of CSPα inhibits SNARE complex formation.
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页码：30 / 39
页数：9
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