Transcriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice

被引:0
作者
Rania Siam
Ryoko Harada
Chantal Cadieux
Robert Battat
Charles Vadnais
Alain Nepveu
机构
[1] McGill University,Goodman Cancer Center
[2] American University in Cairo,Biology Department and The YJ
[3] McGill University,Science and Technology Research Center
[4] McGill University,Department of Biochemistry
[5] McGill University,Department of Oncology
来源
Molecular Cancer | / 8卷
关键词
Transcription Start Site; Mouse Mammary Tumor Virus; Lats1 Expression; Hippo Pathway; Histiocytic Sarcoma;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 327 条
[1]  
Zeng Q(2008)The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals Cancer Cell 13 188-192
[2]  
Hong W(1999)The role of lats in cell cycle regulation and tumorigenesis Biochim Biophys Acta 1424 M9-M16
[3]  
Turenchalk GS(1995)Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase Development (Suppl) 121 1053-1063
[4]  
St John MA(1995)The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation Genes Dev 9 534-546
[5]  
Tao W(1999)Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity Nat Genet 21 177-181
[6]  
Xu T(1999)Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction Nat Genet 21 182-186
[7]  
Xu T(2000)Molecular analysis of the h-warts/LATS1 gene in human breast cancer Int J Oncol 17 1125-1129
[8]  
Wang W(2006)Chromosome 6 deletion and candidate tumor suppressor genes in adenoid cystic carcinoma Cancer Lett 236 309-317
[9]  
Zhang S(2006)Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma Neuroscience Research 56 450-458
[10]  
Stewart RA(2005)Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers Clin Cancer Res 11 1380-1385