Cost Effectiveness of a Lidocaine 5% Medicated Plaster Compared with Pregabalin for the Treatment of Postherpetic Neuralgia in the UKA Markov Model Analysis

被引：0
作者：
Mark Ritchie
Hiltrud Liedgens
Mark Nuijten
机构：
[1] Dr Baker & Partners,Health Economics/Market Access
[2] Grünenthal GmbH,undefined
[3] Erasmus University,undefined
来源：
Clinical Drug Investigation | 2010年 / 30卷
关键词：
Neuropathic Pain; Gabapentin; Pregabalin; Scenario Analysis; Postherpetic Neuralgia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Published analyses have demonstrated that the lidocaine (lignocaine) plaster is a cost-effective treatment for postherpetic neuralgia (PHN) relative to gabapentin or pregabalin. However, these analyses have been based on indirect comparisons from placebo-controlled trials, and there is evidence of a discrepancy between the outcomes of direct and indirect analyses. Fortunately, recent publication of the results of a head-to-head trial comparing the lidocaine plaster and pregabalin in patients with PHN or diabetic polyneuropathy allows customization of the existing model to more accurately reflect the relative cost effectiveness of these two products.
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页码：71 / 87
页数：16
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