1H, 13C and 15N resonance assignments for the tandem CUE domains from chromatin remodeler SMARCAD1

被引：0
作者：
Antonio J. Biasutto
Philip M. West
Erika J. Mancini
Christina Redfield
机构：
[1] University of Oxford,Department of Biochemistry
[2] University of Oxford,Division of Structural Biology, Henry Wellcome Building for Genomic Medicine
[3] University of Sussex,School of Life Sciences, Biomedicine and Biochemistry Department
来源：
Biomolecular NMR Assignments | 2019年 / 13卷
关键词：
CUE domain; SMARCAD1; Chromatin remodelling; ATPase; NMR resonance assignments; Secondary structure;
D O I：
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摘要：
SMARCAD1 is a non-canonical chromatin remodelling ATPase, unique in its domain organization in that is encodes tandem ubiquitin binding CUE domains along with a classical SNF2 helicase ATP-dependent motor. SMARCAD1 is conserved from yeast to humans and has reported roles in the maintenance of heterochromatin following replication and in double-strand break repair. Here we present the 1H, 13C and 15N assignments for the tandem CUE domains and for the disordered regions that flank them. These assignments provide the starting point for detailed investigations of the structure and interactions of this region of SMARCAD1.
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页码：261 / 265
页数：4
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